Extended spectrum of b- lactamase status in Escherichia coli isolated from urinary tract infections in Duhok City- Iraq

Abstract EN

Objectives : To study the pattern of ESβL E.

coli in cross sectional study from urine of patients in Azadi and Heve Paediatric Teaching Hospitals in Duhok city.

Methods : This study was conducted between June 2016 and December 2016.

A study of 325 of E.coli isolates from urine samples in Azadi Teaching Hospital and 420 isolates from Heve Teaching Hospital.

Confirmation of ESβL production was performed using double-disk synergy test and the BD Phoenix automated system..

Results : There were 175 (53.8 %) confirmed strains of ESβLs E.

coli among adults from Azadi Hospital and 163 (38.8 %) strains among paediatrics from Hevi Hospital which were tested by double-disk synergy test and BD Phoenix.

There was no statistical significance for ESβL strains regarding the gender of the patients.

Majority of ESβL E.

coli were among 7-9 years and 25-65 years.

The rate of antibiotic resistance was > 90 % for Ceftazidime, Ceftriaxone, Cefixime, Cefepime, Augmentin and Aztreonam for both adults and paediatric age groups.

The rate of sensitivity for Imipenem, Amikacin and Nitrofurantoin was 4.5 %, 8 % and 16 % respectively for adults and 17 % 15.5 % and 24.5 % for paediatrics respectively.