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E assessment of plasma Von Willebrand factor antigen in non-metastatic prostate cancer patients : a cross-sectional study of the Sudanese population
Joint Authors
Hashim, Muhammad Uthman
Ibrahim, Ibrahim Khidr
Mudawi, Jad Allah
Source
Sudan Journal of Medical Sciences
Issue
Vol. 14, Issue 3 (30 Sep. 2019), pp.97-102, 6 p.
Publisher
Omdurman Islamic University Faculty of Medicine
Publication Date
2019-09-30
Country of Publication
Sudan
No. of Pages
6
Main Subjects
Abstract EN
Backgrounds: Von Willebrand disease (VWD) is reportedly the most common inherited bleeding disorder and can also arise as an acquired syndrome (AVWS).
These disorders arise due to defects and/or deficiency of the plasma protein von Willebrand factor (VWF).
High plasma VWF concentrations have been reported in patients with various types of cancer, such as prostatic cancer.
Metastasization may be associated with activation of hemostatic processes resulting in increased levels of circulating factor VIII-related antigen (FVIIIRAg) (von Willebrand factor antigen).
Objective: To evaluate the status of VWF antigen in Sudanese patients with prostate cancer attending RICK hospital.
Methods: This is a cross-sectional study carried out in Khartoum state at Khartoum oncology (RICK) hospital, during the period from April to June 2018, 45 samples were collected from patients with non-metastatic CA prostate, their ages ranged from 51 to 82 yr.
The VWF level was measured using Enzyme-linked immunosorbent assay (ELISA).
Data were analyzed by the statistical package for social science (SPSS).
Results: Serology for VWF antigen was done for 45 cases of prostate cancer.
According to the age, 2 (8%) patients with age 51–66 yr had a high concentration of VWF, while 24 (92%) had normal VWF antigen concentration; of those with age 67–82 yr, 4 (21%) had high VWF antigen and 15 (79%) had normal antigen.
Conclusion: The study revealed that more than 80% of Sudanese patients with nonmetastatic prostate cancer have a normal concentration of VWF.
American Psychological Association (APA)
Hashim, Muhammad Uthman& Mudawi, Jad Allah& Ibrahim, Ibrahim Khidr. 2019. E assessment of plasma Von Willebrand factor antigen in non-metastatic prostate cancer patients : a cross-sectional study of the Sudanese population. Sudan Journal of Medical Sciences،Vol. 14, no. 3, pp.97-102.
https://search.emarefa.net/detail/BIM-898910
Modern Language Association (MLA)
Hashim, Muhammad Uthman…[et al.]. E assessment of plasma Von Willebrand factor antigen in non-metastatic prostate cancer patients : a cross-sectional study of the Sudanese population. Sudan Journal of Medical Sciences Vol. 14, no. 3 (2019), pp.97-102.
https://search.emarefa.net/detail/BIM-898910
American Medical Association (AMA)
Hashim, Muhammad Uthman& Mudawi, Jad Allah& Ibrahim, Ibrahim Khidr. E assessment of plasma Von Willebrand factor antigen in non-metastatic prostate cancer patients : a cross-sectional study of the Sudanese population. Sudan Journal of Medical Sciences. 2019. Vol. 14, no. 3, pp.97-102.
https://search.emarefa.net/detail/BIM-898910
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references : p. 100-102
Record ID
BIM-898910