The role of Herpes simplex virus type 1 and 2 in patients with neurodegenerative diseases
Other Title(s)
دور فايروس القوباء البسيط النمط الأول و الثاني في المرضى المصابين ببعض الأمراض العصبية
Joint Authors
Hasan, Muhammad Ibrahim
Abbud, Rana Sadi
al-Ahmar, Sayf Dawud
Source
Issue
Vol. 59, Issue 4C (31 Dec. 2018), pp.2179-2183, 5 p.
Publisher
University of Baghdad College of Science
Publication Date
2018-12-31
Country of Publication
Iraq
No. of Pages
5
Main Subjects
Topics
Abstract EN
With the growing number of patient’s being diagnosed with Parkinson’s disease and Multiple Sclerosis each year it is becoming ever more important to find the cause for these neurological disorders.
The present study attempts to shed light on one of the factors that may play a role as a causative agent in these neurological diseases by finding a correlation between the Herpes simplex virus type 1 and 2 in patients with Parkinson’s disease and multiple sclerosis by detecting the virus in these patients using immunological techniques.
Sixty patients with neurological diseases (40 patients with Multiple sclerosis and 20 patients with Parkinson’s disease) who’s ages ranged from (17-76) years have been investigated.
Samples were collected during the time period between November 2017 and April 2018 and compared to twenty five apparently healthy individuals as a control group.
All the studied groups were measured for herpes simplex virus type-1 IgM and herpes simplex virus type-2 IgM by using the enzyme linked immuno sorbent assay.
The results of the present study showed that there was a highly significant difference (p<0.01) in the concentration of IgM HSV-1 and HSV-2 in the sera of patients with MS and PD compared to the control group, While there was a none-significant difference (p>0.05) in the concentration of IgM HSV-1 and HSV-2 according to the gender.
Thus, there is a likely possibility the HSV could be a contributing factor in the activation of some neurological diseases by the means of initiating an autoimmune reaction against the host’s nerve cells.
The nerve cells have proteins that resemble portions of the virus from a structural and genetic stand point.
American Psychological Association (APA)
Hasan, Muhammad Ibrahim& Abbud, Rana Sadi& al-Ahmar, Sayf Dawud. 2018. The role of Herpes simplex virus type 1 and 2 in patients with neurodegenerative diseases. Iraqi Journal of Science،Vol. 59, no. 4C, pp.2179-2183.
https://search.emarefa.net/detail/BIM-899033
Modern Language Association (MLA)
Hasan, Muhammad Ibrahim…[et al.]. The role of Herpes simplex virus type 1 and 2 in patients with neurodegenerative diseases. Iraqi Journal of Science Vol. 59, no. 4C (2018), pp.2179-2183.
https://search.emarefa.net/detail/BIM-899033
American Medical Association (AMA)
Hasan, Muhammad Ibrahim& Abbud, Rana Sadi& al-Ahmar, Sayf Dawud. The role of Herpes simplex virus type 1 and 2 in patients with neurodegenerative diseases. Iraqi Journal of Science. 2018. Vol. 59, no. 4C, pp.2179-2183.
https://search.emarefa.net/detail/BIM-899033
Data Type
Journal Articles
Language
English
Notes
Text in English ; abstracts in English and Arabic.
Record ID
BIM-899033