Synthesis and study of many new Chalcone derivatives
Other Title(s)
تحضير و دراسة عدد من مشتقات الجالكون الجديدة
Joint Authors
Ahmad, Natiq Ghanim
Ali, Murtada H.
Source
al-Tarbiyah wa-al-Ilm : Majallat ilmiyah lil-Buhuth al-Ilmiyah al-Asasiyah
Issue
Vol. 27, Issue 4 (31 Dec. 2018), pp.1-28, 28 p.
Publisher
University of Mosul College of Education for Pure Science
Publication Date
2018-12-31
Country of Publication
Iraq
No. of Pages
28
Main Subjects
Abstract EN
This study include the synthesis of the compound 1-(1H-benzo[d]imidazol-2-yl)ethanol [1], from the reaction of ortho pheneylene diamine with lactic acid and then oxidized using potassium dichromate to give1-(1H-benzo[d]imidazol-2-yl) ethanone [2].
Reaction of this compound with different substituted benzaldehydes or 1-(1H-benzo[d]imidazol-2-yl)ethanone, to obtain α, β-unsaturated carbonyl compounds (chalcones) [3-11].
These chalcones have been used in preparing number of heterocyclic compounds through reaction with the hydrogen peroxide to get the oxiran compounds (three membered rings) [12-20], hydroxyl amine hydrochloride to prepare the isooxazoline compounds(five membered rings) [21-29], 3-nitrobenzohydrazide to prepare the pyrazoline compounds(five membered rings)[30-38], thiosemicarbazide hydrochloride to prepare the pyrazoline compounds(five membered rings) [39-47], semicarbazide to prepare the pyrazoline compounds(five membered rings) [48-56], guanidine nitrate to prepare the pyrimidine compounds(six membered rings) [57-65], ortho pheneylenediamine to prepare the benzodiazepine compounds (seven membered rings) [66-74], ortho aminophenol to prepare the benzoxazepine compounds(seven membered rings) [75-83].
The synthesized compounds were identified, using chemical, physical and spectral methods (melting points, color change, infrared spectra, ultraviolet spectra, nuclear magnetic resonance spectra and many theoretical studies).
American Psychological Association (APA)
Ahmad, Natiq Ghanim& Ali, Murtada H.. 2018. Synthesis and study of many new Chalcone derivatives. al-Tarbiyah wa-al-Ilm : Majallat ilmiyah lil-Buhuth al-Ilmiyah al-Asasiyah،Vol. 27, no. 4, pp.1-28.
https://search.emarefa.net/detail/BIM-899277
Modern Language Association (MLA)
Ahmad, Natiq Ghanim& Ali, Murtada H.. Synthesis and study of many new Chalcone derivatives. al-Tarbiyah wa-al-Ilm : Majallat ilmiyah lil-Buhuth al-Ilmiyah al-Asasiyah Vol. 27, no. 4 (2018), pp.1-28.
https://search.emarefa.net/detail/BIM-899277
American Medical Association (AMA)
Ahmad, Natiq Ghanim& Ali, Murtada H.. Synthesis and study of many new Chalcone derivatives. al-Tarbiyah wa-al-Ilm : Majallat ilmiyah lil-Buhuth al-Ilmiyah al-Asasiyah. 2018. Vol. 27, no. 4, pp.1-28.
https://search.emarefa.net/detail/BIM-899277
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references : p. 26-28
Record ID
BIM-899277