Colorimetric determination of meprobamate after a simple derivatization
Joint Authors
al-Janabi, Khalid Walid Salih
Sabir, Nur al-Huda Ahmad
Source
Ibn al-Haitham Journal for Pure and Applied Science
Issue
Vol. 32, Issue 3 (31 Dec. 2019), pp.62-69, 8 p.
Publisher
University of Baghdad College of Education for Pure Science / Ibn al-Haitham
Publication Date
2019-12-31
Country of Publication
Iraq
No. of Pages
8
Main Subjects
Abstract EN
sensitive and environmentally benign spectrometric method was developed for quantifying Meprobamate (MEP).
The analyzed MEP was derivatized into a colored complex and determined spectrometrically.
The colorimetric analytical parameters were optimized and validated.
Low limit of detection (LOD) was achieved down to 1.88×10-6 mol/l while the limit of quantification (LOQ) was extended over the range of 1.97×10-6 - 1.35×10-3 mol/l.
The high precision has been denoted by the 1.54% value of the coefficient of variation.
The recovery was 96.07%, while the RSD (n=3) was 1.05 - 1.19%.
The apparent molar absorptivity (Ɛ) obtained within 1154.7 - 1691.9 L.mol-1.cm-1.
The outcomes have signified the high sensitivity of the technique.
Furthermore, the avoidance of any traditional sample preparation steps prior to the analysis makes the method an excellent environmental approach.
There were no analytical interferences with the common composites.
The method has been successfully verified for the quantification of MEP content in bulk pharmaceutical matrix and can be applied to determine other environmentally toxic carbamates
American Psychological Association (APA)
Sabir, Nur al-Huda Ahmad& al-Janabi, Khalid Walid Salih. 2019. Colorimetric determination of meprobamate after a simple derivatization. Ibn al-Haitham Journal for Pure and Applied Science،Vol. 32, no. 3, pp.62-69.
https://search.emarefa.net/detail/BIM-899936
Modern Language Association (MLA)
Sabir, Nur al-Huda Ahmad& al-Janabi, Khalid Walid Salih. Colorimetric determination of meprobamate after a simple derivatization. Ibn al-Haitham Journal for Pure and Applied Science Vol. 32, no. 3 (Dec. 2019), pp.62-69.
https://search.emarefa.net/detail/BIM-899936
American Medical Association (AMA)
Sabir, Nur al-Huda Ahmad& al-Janabi, Khalid Walid Salih. Colorimetric determination of meprobamate after a simple derivatization. Ibn al-Haitham Journal for Pure and Applied Science. 2019. Vol. 32, no. 3, pp.62-69.
https://search.emarefa.net/detail/BIM-899936
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references : p. 68-69
Record ID
BIM-899936