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Toxico-pathological study of gentamicin by intramuscular injection in experimental rabbits
Other Title(s)
دراسة سمية-إمراضية الحقن العضلي للجنتاميسين سلفات في الأرانب المختبرية
Joint Authors
Abd, Ala Tariq
Majid, Salih Kazim
Hasan, Muhammad Abd al-Abbas
Khudayr, Zaynab Wahid
Source
Basrah Journal of Veterinary Research
Issue
Vol. 17, Issue 2 (31 Dec. 2018), pp.1-13, 13 p.
Publisher
University of Basrah College of Veterinary Medicine
Publication Date
2018-12-31
Country of Publication
Iraq
No. of Pages
13
Main Subjects
Abstract EN
In the current study, 16 rabbit was divided into two groups.
Animals of Group I (untreated control) were maintained without any treatment.
Group 2 animals (treated group), the gentamicin were injected in thigh muscle /I.M.
at 25 mg/kg body weight twice a day (morning and evening) for two months.
During experimental period anorexia, emaciation, and death some animals were seen.
Histopathological examination showed that there was proliferated of cortical renal tubules cells and degeneration with necrosis of some them as well as congestion of sinusoid in liver and proliferation of bile duct.
There was also vacuolated and congestion of myocardial tissue.
In conclusion, the administration of gentamycin for long time could serve as a source of harm to animal organs such as kidney, liver, bile duct, and heart
American Psychological Association (APA)
Majid, Salih Kazim& Khudayr, Zaynab Wahid& Hasan, Muhammad Abd al-Abbas& Abd, Ala Tariq. 2018. Toxico-pathological study of gentamicin by intramuscular injection in experimental rabbits. Basrah Journal of Veterinary Research،Vol. 17, no. 2, pp.1-13.
https://search.emarefa.net/detail/BIM-900446
Modern Language Association (MLA)
Majid, Salih Kazim…[et al.]. Toxico-pathological study of gentamicin by intramuscular injection in experimental rabbits. Basrah Journal of Veterinary Research Vol. 17, no. 2 (2018), pp.1-13.
https://search.emarefa.net/detail/BIM-900446
American Medical Association (AMA)
Majid, Salih Kazim& Khudayr, Zaynab Wahid& Hasan, Muhammad Abd al-Abbas& Abd, Ala Tariq. Toxico-pathological study of gentamicin by intramuscular injection in experimental rabbits. Basrah Journal of Veterinary Research. 2018. Vol. 17, no. 2, pp.1-13.
https://search.emarefa.net/detail/BIM-900446
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references : p. 11-13
Record ID
BIM-900446