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Comparative study of thymidine kinase -1 and total antioxidant capacity in Iraqi children with platelet count disorder
Joint Authors
Abbas, Iman A. A.
Jabr, Manar Sattar
Source
Ibn al-Haitham Journal for Pure and Applied Science
Issue
Vol. 31, Issue 3 (31 Dec. 2018), pp.79-87, 9 p.
Publisher
University of Baghdad College of Education for Pure Science / Ibn al-Haitham
Publication Date
2018-12-31
Country of Publication
Iraq
No. of Pages
9
Main Subjects
Abstract EN
This study aimed to find relationship between thymidine kinase-1 (TK-1) as tumor marker and total antioxidant capacity (TAC) in Iraqi children patients with thrombocytopenia and with thrombocytosis.
The present study conducted 60 children patients (30 patients with idiopathic thrombocytopenia purpura (ITP) and 30 patients with thrombocytosis caused by leukemia) attending the Children Fever Hospital in the Medical City / Baghdad, and 30 healthy children as a control group.
All study groups were with range ages (1-15) years, and they were diagnosed by assay of platelet count, Prothrombin Time (PT), and partial Thromboplastin Time (PTT).
The results shown elevation in plasma TK-1 and TAC values in children patients with thrombocytopenia and with thrombocytosis when compared with control group, and there was no significant different in TK-1 level and a significant different in TAC level in two patient’s groups.
There was a highly significant positive correlation between TK-1 and TAC levels in both Iraqi children patients with thrombocytopenia and with thrombocytosis.
The current study concluded that TK-1 may be a novel biomarker for platelet count disorder disease and there was a probability of expose these patients for tumor diseases.
American Psychological Association (APA)
Jabr, Manar Sattar& Abbas, Iman A. A.. 2018. Comparative study of thymidine kinase -1 and total antioxidant capacity in Iraqi children with platelet count disorder. Ibn al-Haitham Journal for Pure and Applied Science،Vol. 31, no. 3, pp.79-87.
https://search.emarefa.net/detail/BIM-900656
Modern Language Association (MLA)
Jabr, Manar Sattar& Abbas, Iman A. A.. Comparative study of thymidine kinase -1 and total antioxidant capacity in Iraqi children with platelet count disorder. Ibn al-Haitham Journal for Pure and Applied Science Vol. 31, no. 3 (2018), pp.79-87.
https://search.emarefa.net/detail/BIM-900656
American Medical Association (AMA)
Jabr, Manar Sattar& Abbas, Iman A. A.. Comparative study of thymidine kinase -1 and total antioxidant capacity in Iraqi children with platelet count disorder. Ibn al-Haitham Journal for Pure and Applied Science. 2018. Vol. 31, no. 3, pp.79-87.
https://search.emarefa.net/detail/BIM-900656
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references : p. 85-87
Record ID
BIM-900656