Potency Syzygium cumini L as adjuvant therapy on mice model malaria
Other Title(s)
كفاءة البامبوزيا كعامل مساعد في علاج الملاريا نموذج الفئران
Joint Authors
Maslachah, Lilak
Sugihartuti, Rahimi
Source
Iraqi Journal of Veterinary Sciences
Issue
Vol. 32, Issue 1 (30 Jun. 2018), pp.73-80, 8 p.
Publisher
University of Mosul College of Veterinary Medicine
Publication Date
2018-06-30
Country of Publication
Iraq
No. of Pages
8
Main Subjects
Topics
Abstract EN
The objective of the study was to prove the potential extract of Syzygium cumini L leaf and stem bark as an adjuvant to malaria modelling mice.
Antimalarial effects were assessed by the percentage of parasitemia, growth inhibition, 50% dose level (ED50), Parasite Clearance Time (PCT), Recrudescence Time (RT) of Plasmodium berghei.
Male albino Swiss mice infected with lxlO5 P.
berghei parasite in 0.2 ml intraperitoneally.
Treatment with chloroquine 25 mg/kg body weight, chloroquine combination 25 mg/kg body weight with leaf and stem bark extract of Syzygium cumini L dose 600 mg / kg body weight for 4 days and 24 hours after infection, and then its activity as antimalarial and adjuvant therapy were observed.
The results showed that the extract of Syzygium cumini L leaf combined with chloroquine gives highly significant result in inhibiting the growth of parasites than the chloroquine alone and the extract of Syzygium cumini L leaf combined with chloroquine gives the Parasite Clearance Time faster and Recrudescence Time (RT) longer than the other treatment.
American Psychological Association (APA)
Maslachah, Lilak& Sugihartuti, Rahimi. 2018. Potency Syzygium cumini L as adjuvant therapy on mice model malaria. Iraqi Journal of Veterinary Sciences،Vol. 32, no. 1, pp.73-80.
https://search.emarefa.net/detail/BIM-900698
Modern Language Association (MLA)
Maslachah, Lilak& Sugihartuti, Rahimi. Potency Syzygium cumini L as adjuvant therapy on mice model malaria. Iraqi Journal of Veterinary Sciences Vol. 32, no. 1 (2018), pp.73-80.
https://search.emarefa.net/detail/BIM-900698
American Medical Association (AMA)
Maslachah, Lilak& Sugihartuti, Rahimi. Potency Syzygium cumini L as adjuvant therapy on mice model malaria. Iraqi Journal of Veterinary Sciences. 2018. Vol. 32, no. 1, pp.73-80.
https://search.emarefa.net/detail/BIM-900698
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references : p. 80
Record ID
BIM-900698