Effects of autologous platelet-rich plasma on skin healing in dogs
Other Title(s)
تأثير البلازما الغنية بالصفائح الدموية الذاتية على شفاء الجلد في الكلاب
Author
Source
Iraqi Journal of Veterinary Sciences
Issue
Vol. 32, Issue 2 (31 Dec. 2018), pp.281-289, 9 p.
Publisher
University of Mosul College of Veterinary Medicine
Publication Date
2018-12-31
Country of Publication
Iraq
No. of Pages
9
Main Subjects
Abstract EN
This study aimed to evaluate the benefits of using platelet- rich plasma (PRP) on wound healing.
The study performed on ten adult male dogs, aged 2-3 years and their weight were 18-25 kg.
Under the effect of deep sedation and local subcutaneous anesthesia at the site of wound, four of (2x2) cm of full-thickness square cutaneous wounds were induced, two on each side of the lateral thoracic region of each animal.
A pair of left wounds was treated by injection with 5 mL of autonomous PRP (treatment group).
2 mm lateral to the wound edges and in the wound center., immediately after wounding while, right wounds, were injected with a single dose of 5ml of sterile saline (control group) by using the same procedure as in treatment group.
The clinical and lustopathological evaluation of each group for five weeks, histological biopsies were taken in the days (3, 7, 14, 21, 28 and 35) of the experiment.
The clinical evaluation of PRP treated wounds showed that the wound healing process (% contraction.
% re-epithelization and % total wound healing) were significantly more (P;:0.05) than the control wounds dining the five weeks study.
The histopathological results revealed that PRP treated wounds have enhanced cellulanty.
increased vascularity, with increased amount of granulation tissue accompanied by increase numbers of skin appendages suggesting enhanced cutaneous regeneration, than those in untreated wounds.
Depending on the clinical and histopathological findings, this study confirms that local implantation of PRP leads to acceleration and improvement cutaneous wound healing
American Psychological Association (APA)
Husayn, Sinaa Malik. 2018. Effects of autologous platelet-rich plasma on skin healing in dogs. Iraqi Journal of Veterinary Sciences،Vol. 32, no. 2, pp.281-289.
https://search.emarefa.net/detail/BIM-901014
Modern Language Association (MLA)
Husayn, Sinaa Malik. Effects of autologous platelet-rich plasma on skin healing in dogs. Iraqi Journal of Veterinary Sciences Vol. 32, no. 2 (2018), pp.281-289.
https://search.emarefa.net/detail/BIM-901014
American Medical Association (AMA)
Husayn, Sinaa Malik. Effects of autologous platelet-rich plasma on skin healing in dogs. Iraqi Journal of Veterinary Sciences. 2018. Vol. 32, no. 2, pp.281-289.
https://search.emarefa.net/detail/BIM-901014
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references : p. 288-289
Record ID
BIM-901014