Effect of helicobacter pylori eradicationon the pathogenesis of minimal hepatic encephalopathy in Egyptian patients with liver cirrhosis
Joint Authors
Amir, Muhyi al-Din
Abd al-Khaliq, Muhammad Abd al-Rashid
Khidr, Muhammad Abd al-Hamid Basyuni
Masud, Safwat Ahmad Muhammad Ali
Source
Journal of the Egyptian Society of Parasitology
Issue
Vol. 48, Issue 3 (31 Dec. 2018), pp.583-598, 16 p.
Publisher
The Egyptian Society of Parasitology
Publication Date
2018-12-31
Country of Publication
Egypt
No. of Pages
16
Main Subjects
Topics
Abstract EN
Hepatic encephalopathy is one of the complications of liver cirrhosis.
Ammonia is implicated as a precipitating factor for HE, minimal hepatic encephalopathy cannot be detected clinically and impairs quality of life, indicated that H.
pylori infection is associated with high blood ammonia levels by urease enzyme and can lead to causation of HE.
This study evaluated the effect of H.
pylori eradication therapy on MHE.
A total of 60 cirrhotic patients were selected from al-Hussein University Hospital.
They were GI: 30 patients with MHE and GII; 30 patients without MHE.
All patients were subjected to H.
pylori stool antigen and blood ammonia level.
Positive H.
pylori patients received triple therapy for 14 days, then 4 weeks later were revaluated regarding, H.
pylori stool antigen, serum ammonia level and NCT.
Helicobacter pylori infection was found 63.3% of GI versus 40% in GII; serum ammonia levels were significantly higher in patients with GI and H.
pylori positive.
Treatment was successful in 78.9% of GI patients versus 89.4% of GII.
Number connection test and serum ammonia level were significantly improved in GI patients and positive H.
pylori after eradication therapy.
American Psychological Association (APA)
Amir, Muhyi al-Din& Abd al-Khaliq, Muhammad Abd al-Rashid& Khidr, Muhammad Abd al-Hamid Basyuni& Masud, Safwat Ahmad Muhammad Ali. 2018. Effect of helicobacter pylori eradicationon the pathogenesis of minimal hepatic encephalopathy in Egyptian patients with liver cirrhosis. Journal of the Egyptian Society of Parasitology،Vol. 48, no. 3, pp.583-598.
https://search.emarefa.net/detail/BIM-901262
Modern Language Association (MLA)
Amir, Muhyi al-Din…[et al.]. Effect of helicobacter pylori eradicationon the pathogenesis of minimal hepatic encephalopathy in Egyptian patients with liver cirrhosis. Journal of the Egyptian Society of Parasitology Vol. 48, no. 3 (Dec. 2018), pp.583-598.
https://search.emarefa.net/detail/BIM-901262
American Medical Association (AMA)
Amir, Muhyi al-Din& Abd al-Khaliq, Muhammad Abd al-Rashid& Khidr, Muhammad Abd al-Hamid Basyuni& Masud, Safwat Ahmad Muhammad Ali. Effect of helicobacter pylori eradicationon the pathogenesis of minimal hepatic encephalopathy in Egyptian patients with liver cirrhosis. Journal of the Egyptian Society of Parasitology. 2018. Vol. 48, no. 3, pp.583-598.
https://search.emarefa.net/detail/BIM-901262
Data Type
Journal Articles
Language
English
Notes
Includes appendix : p. 597-598
Record ID
BIM-901262