Effect of synthesized oxiranes and pyrrolidines on KMP II and LPG 3 genes in Leishmania infantum promastigotes
Other Title(s)
تأثير الأوكسيرانات و البايروليدينات المشيدة على جيني KMP II و LPG 3 في بروماستكوت اللشمانيا الأحشائية L. infantum
Joint Authors
al-Qattan, Muntaha M.
al-Hamdani, Abd al-Wahhab J.
al-Hiyali, Haytham L.
Source
Issue
Vol. 27, Issue 3 (30 Jun. 2018), pp.35-46, 12 p.
Publisher
University of Mosul College of Science
Publication Date
2018-06-30
Country of Publication
Iraq
No. of Pages
12
Main Subjects
Topics
Abstract EN
The research includes synthesis of some heterocycles: oxiranes (O1-O3) through the reaction of chalcones with hydrogen peroxide, and pyrrolidines (P1-P3) by the condensation of chalcones with Schiff bases.
The structures of these synthesized heterocycles had been supported by spectral data (1HNMR, IR, UV) and observed their effect on KMP II and LPG 3 genes.
The results showed that some compounds gave genetic heterogeneity in these genes suggesting that it could be a good target for treatment of L.
infantum.
American Psychological Association (APA)
al-Hiyali, Haytham L.& al-Hamdani, Abd al-Wahhab J.& al-Qattan, Muntaha M.. 2018. Effect of synthesized oxiranes and pyrrolidines on KMP II and LPG 3 genes in Leishmania infantum promastigotes. Rafidain Journal of Science،Vol. 27, no. 3, pp.35-46.
https://search.emarefa.net/detail/BIM-901329
Modern Language Association (MLA)
al-Hiyali, Haytham L.…[et al.]. Effect of synthesized oxiranes and pyrrolidines on KMP II and LPG 3 genes in Leishmania infantum promastigotes. Rafidain Journal of Science Vol. 27, no. 3 (2018), pp.35-46.
https://search.emarefa.net/detail/BIM-901329
American Medical Association (AMA)
al-Hiyali, Haytham L.& al-Hamdani, Abd al-Wahhab J.& al-Qattan, Muntaha M.. Effect of synthesized oxiranes and pyrrolidines on KMP II and LPG 3 genes in Leishmania infantum promastigotes. Rafidain Journal of Science. 2018. Vol. 27, no. 3, pp.35-46.
https://search.emarefa.net/detail/BIM-901329
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references : p. 44-46
Record ID
BIM-901329
