The Antifibrotic potential of resveratrol in Schistosoma Mansoni-infected mice
Joint Authors
al-Hamshari, Iman M.
Sulayman, Rasha H.
Ismail, O. A.
Husayni, A. H.
Source
Journal of the Egyptian Society of Parasitology
Issue
Vol. 48, Issue 1 (30 Apr. 2018), pp.1-13, 13 p.
Publisher
The Egyptian Society of Parasitology
Publication Date
2018-04-30
Country of Publication
Egypt
No. of Pages
13
Main Subjects
Abstract EN
Schistosoma mansoni infection continues to be one of the most serious parasitosis worldwide due to its debilitating effects, mainly hepatic fibrosis.
The present study explored the antifibrotic effect of resveratrol (RSV), either alone or in combination with praziquantel, on the murine model of intestinal schistosomiasis.
We performed two parallel experiments exploring the preventive and the curative effect of RSV on inflammation and fibrosis.
Parasitological measurements (adult worm burden, oogram), biochemical (AST, ALT, hydroxyproline), histopathological and histobiochemical studies were performed.
The results revealed that RSV has significant curative and preventive outcome on hepatic fibrosis and this effect is augmented when coupled with praziquantel.
Other parasitological and biochemical parameters were enhanced as well.
American Psychological Association (APA)
Sulayman, Rasha H.& Ismail, O. A.& al-Hamshari, Iman M.& Husayni, A. H.. 2018. The Antifibrotic potential of resveratrol in Schistosoma Mansoni-infected mice. Journal of the Egyptian Society of Parasitology،Vol. 48, no. 1, pp.1-13.
https://search.emarefa.net/detail/BIM-901548
Modern Language Association (MLA)
Sulayman, Rasha H.…[et al.]. The Antifibrotic potential of resveratrol in Schistosoma Mansoni-infected mice. Journal of the Egyptian Society of Parasitology Vol. 48, no. 1 (Apr. 2018), pp.1-13.
https://search.emarefa.net/detail/BIM-901548
American Medical Association (AMA)
Sulayman, Rasha H.& Ismail, O. A.& al-Hamshari, Iman M.& Husayni, A. H.. The Antifibrotic potential of resveratrol in Schistosoma Mansoni-infected mice. Journal of the Egyptian Society of Parasitology. 2018. Vol. 48, no. 1, pp.1-13.
https://search.emarefa.net/detail/BIM-901548
Data Type
Journal Articles
Language
English
Notes
Includes appendices : p. 11-13
Record ID
BIM-901548