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Protein carbonyl, oxidative stress, anemia, total free amino acids and sheep haemonchosis relationship
Joint Authors
Kamil, Hamdi H.
Mustafa, al-Hasan M.
al-salahi, Muhammad B.
M. S. Walaa
Wahbah, Ahmad A.
Source
Journal of the Egyptian Society of Parasitology
Issue
Vol. 48, Issue 1 (30 Apr. 2018), pp.21-30, 10 p.
Publisher
The Egyptian Society of Parasitology
Publication Date
2018-04-30
Country of Publication
Egypt
No. of Pages
10
Main Subjects
Abstract EN
The present study estimated oxidant/antioxidant status in blood of sheep naturally infested with Haemonchus contortus.
Blood samples from infected and healthy (control) sheep were used to determine hematological, some antioxidants and biochemical parameters.
The sheep showed microcytic hypochromic anemia.
Haemonchosis in sheep resulted in a significant stimulation in MDA snd PC.
By contrast, a significant inhibition of the antioxidants activity of both SOD and GSH coupled with a significant inhibition of both ceruloplasmin (CP), Total Iron (Fe) and Copper (Cu) in infected sheep.
In turn, a significant stimulation in CAT activity and in TFAA in infected sheep compared to control values was detected.
The results showed a significant positive correlation between the increasing level of PC with the stimulating levels of MDA (r = 0.47, R2 = 0.22, P = 0.02), CAT activity ( r= 0.60, R2 = 0.37, P = 0.001), TFAA in plasma (r = 0.46, R2 = 0.21, P = 0.03) and EP (r = 0.43, R2=0.19, P=0.04).
By contrast, stimulated level of PC was inversely correlated with diminished values of SOD (r = -0.55, R2 = 0.31, P = 0.03), Hb (r = -0.43, R2 = 0.19, P = 0.04) and PCV % (r = -0.65, R2 = 0.42, P = 0.003).
Haemonchosis was accompanied by disturbances in protein synthesis and a general oxidative damage.
American Psychological Association (APA)
Kamil, Hamdi H.& Mustafa, al-Hasan M.& al-salahi, Muhammad B.& M. S. Walaa& Wahbah, Ahmad A.. 2018. Protein carbonyl, oxidative stress, anemia, total free amino acids and sheep haemonchosis relationship. Journal of the Egyptian Society of Parasitology،Vol. 48, no. 1, pp.21-30.
https://search.emarefa.net/detail/BIM-901555
Modern Language Association (MLA)
Kamil, Hamdi H.…[et al.]. Protein carbonyl, oxidative stress, anemia, total free amino acids and sheep haemonchosis relationship. Journal of the Egyptian Society of Parasitology Vol. 48, no. 1 (Apr. 2018), pp.21-30.
https://search.emarefa.net/detail/BIM-901555
American Medical Association (AMA)
Kamil, Hamdi H.& Mustafa, al-Hasan M.& al-salahi, Muhammad B.& M. S. Walaa& Wahbah, Ahmad A.. Protein carbonyl, oxidative stress, anemia, total free amino acids and sheep haemonchosis relationship. Journal of the Egyptian Society of Parasitology. 2018. Vol. 48, no. 1, pp.21-30.
https://search.emarefa.net/detail/BIM-901555
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references : p. 28-30
Record ID
BIM-901555