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C-reactive protein and adiposity in women with polycystic ovary syndrome
Other Title(s)
بروتين سي التفاعلي و السمنة في النساء المصابات بمتلازمة تكيس المبايض
Author
Source
Journal of Medical and Pharmaceutical Sciences
Issue
Vol. 2, Issue 1 (31 Mar. 2018), pp.19-27, 9 p.
Publisher
Publication Date
2018-03-31
Country of Publication
Palestine (Gaza Strip)
No. of Pages
9
Main Subjects
Abstract EN
C-reactive protein (CRP) is one of the biomarkers that elevated in obese women with polycystic ovary syndrome (PCOS).
PCOS is the most common endocrine disorder, affecting 5-10 % of women at reproductive age.
This syndrome is characterized by overproduction of androgen and ovulatory dysfunction which are accompanied by many clinical and biochemical features including hirsutism, acne, ovary cysts, menstrual irregularities, obesity, dyslipidemia, hyperinsulinemia and glucose intolerance.
This study was aimed to: 1.
measure serum levels of CRP, total cholesterol, triglyceride, LDL, HDL, VHDL, in addition to calculate Body Mass Index (BMI), in women with PCOS and to compare the results with that of healthy women (Controls).
2.
Compare serum CRP, total cholesterol, triglyceride, LDL, HDL and VHDL in patient subgroups with BMI matched control subgroups.
The present study includes thirty (30) women with PCOS and thirty (30) healthy women served as control.
All subjects' age range was between 15 to 40 years, then each group classified into two subgroups depending on BMI.
Blood samples were collected and serum was obtained to measure CRP and lipid profile.
Polycystic ovarian women group exhibited significantly increased serum levels of CRP (p = 0.001), cholesterol (p = 0.009), triglyceride (p =0.0001) and LDL (p = 0.0001) when compared to healthy control group.
BMI also increased in polycystic ovarian women group although it is statistically not significant when compared to controls.
Our results indicated that CRP is one of biomarkers in obese women with PCOS.
Its high level associated with adiposity rather than PCOS itself.
American Psychological Association (APA)
Fathi, Fatimah Haytham. 2018. C-reactive protein and adiposity in women with polycystic ovary syndrome. Journal of Medical and Pharmaceutical Sciences،Vol. 2, no. 1, pp.19-27.
https://search.emarefa.net/detail/BIM-902429
Modern Language Association (MLA)
Fathi, Fatimah Haytham. C-reactive protein and adiposity in women with polycystic ovary syndrome. Journal of Medical and Pharmaceutical Sciences Vol. 2, no. 1 (Mar. 2018), pp.19-27.
https://search.emarefa.net/detail/BIM-902429
American Medical Association (AMA)
Fathi, Fatimah Haytham. C-reactive protein and adiposity in women with polycystic ovary syndrome. Journal of Medical and Pharmaceutical Sciences. 2018. Vol. 2, no. 1, pp.19-27.
https://search.emarefa.net/detail/BIM-902429
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references : p. 25-26
Record ID
BIM-902429