Interventricular mechanical dyssynchrony in dilated cardiomyopathy and its relation with left ventricular systolic dysfunction

Abstract EN

Background: Heart failure (HF) is a major problem worldwide, and despite the optimal medical treatment, still it carries high mortality.Ventricular dyssynchrony among patient with HF portends poor prognosis.

Aim of the Study: The aim is to evaluate the prevalence ofinterventricular dyssynchrony in patients with dilated cardiomyopathy (DCM) patients and its relation to underlying etiology and the severityof systolic dysfunction.

Materials and Methods: Fifty‑eight patients with ischemic and nonischemic cardiomyopathy (ICM and NCM) wereincluded in this study.

Inclusion criteria include Type II–IV New York Heart Association patients with ejection fraction (EF) <35%.

Mechanicaldyssynchrony (interventricular dyssynchrony) was assessed by pulsed Doppler.

Assessment of left ventricular (LV) systolic function was byEF and stroke volume.

Evaluation of the prevalence of mechanical indices in DCM and their relation to underlying etiology and severityof LV systolic dysfunction was done.

Results: The prevalence of interventricular dyssynchrony was more in NCM than ICM.

There was anonsignificant negative correlation between this dyssynchrony and LV systolic parameters.

Conclusion: Mechanical dyssynchrony indiceswere affected by the underlying etiology and severity of LV systolic dysfunction associated with the existence of the mechanical dyssynchrony.