Studying levels of homocysteine in diagnosed cases of polycystic ovary syndrome
Joint Authors
Sulayman, Diya Mustafa
Sulayman, Rujin Rashid
Source
Issue
Vol. 15, Issue 4 (31 Dec. 2018), pp.291-294, 4 p.
Publisher
University of Babylon College of Medicine
Publication Date
2018-12-31
Country of Publication
Iraq
No. of Pages
4
Main Subjects
Abstract EN
: Polycystic ovary syndrome (PCOS) is an endocrine disorder characterized by an ovulatory infertility, menstrual dysfunction, and hirsutism.
The pathophysiology behind PCOS is complex.
Comorbidities associated with PCOS are hypertension, diabetes, dyslipidemia, and cardiovascular events.
Objective: The aim of this study was to estimate the level of homocysteine in women with PCOS.
Materials and Methods: In the current case–control study, 50 female patients diagnosed with PCOS and 40 apparently healthy controls were recruited.
The diagnosis of PCOS was established according to Rotterdam criteria.
The serum homocysteine level was measured using Cobas 6000 and compared between two study groups.
Results: Results found that high percentage of patients in the case group had abnormal level of homocysteine (74.0%) compared to control with normal level of homocysteine.
Mean homocysteine level was significantly higher in patients with PCOS (17 μmol/L) compared to its level in control patients (9 μmol/L), P < 0.0001.
Results also revealed that the mean levels of homocysteine between the body mass index categories and marital status showed no significant difference in cases and controls, P > 0.05.
Conclusions: The present investigation suggests that higher level of serum homocysteine could be used as a biomarker for PCOS.
American Psychological Association (APA)
Sulayman, Rujin Rashid& Sulayman, Diya Mustafa. 2018. Studying levels of homocysteine in diagnosed cases of polycystic ovary syndrome. Medical Journal of Babylon،Vol. 15, no. 4, pp.291-294.
https://search.emarefa.net/detail/BIM-902626
Modern Language Association (MLA)
Sulayman, Rujin Rashid& Sulayman, Diya Mustafa. Studying levels of homocysteine in diagnosed cases of polycystic ovary syndrome. Medical Journal of Babylon Vol. 15, no. 4 (Oct. / Dec. 2018), pp.291-294.
https://search.emarefa.net/detail/BIM-902626
American Medical Association (AMA)
Sulayman, Rujin Rashid& Sulayman, Diya Mustafa. Studying levels of homocysteine in diagnosed cases of polycystic ovary syndrome. Medical Journal of Babylon. 2018. Vol. 15, no. 4, pp.291-294.
https://search.emarefa.net/detail/BIM-902626
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references : p. 293-294
Record ID
BIM-902626