Relative biophysical effects on rat's bone as a result of high energy photons and electromagnetic fields exposures

Abstract EN

There is critical need to do a lot of experimental studies to calculate of the relative biological effects of non-ionizing radiation and comparing its effect with ionizing radiation to re-determine the safe exposure dose to non-ionizing radiation.

this research is concerned with studying the relative fraction of damage (RFD) of the extremely low frequency electromagnetic fields (4kv/m -50 Hz) to high energy photons (6 MEV) on some biophysical properties of rats bone.

in this regard, 100 male albino rats are used and divided into sub groups of 10 rats each.

one group of animals was used as control group (unexposed group) and did not receive any treatment.

similar to occupational workers, four groups of animals were exposed 8h/day for periods from 1 to 4 weeks and were immediately sacrificed at the end of the exposure period.

four groups of animals exposed 8h/day for periods from 1 to 4 weeks and remained 45 days post exposure periods, then sacrificed.

the last group of animals was exposed to a high energy dose of6 MEV of dose (1rad).

femur bone samples of each animal from all groups were collected and prepared for further biophysical investigations.

in addition, RFD of magnetic fields exposures are calculated for each group relative to dose of 6 mev-1 rad photons.

results of exposure to the electric field showed significant deterioration effect on the biomechanical parameters of femurs as a consequential defect of bone strength and bone quality as compared to the unexposed ones.

also, the results obtained from the groups that udergone a post exposure period of 45-days did not show amendment in bone biophysical characteristics, which means that permanent effects and chronic damage of bone tissues may have resulted.

on the other hand, the RFD ratios illustrated that the effect of exposure to elf EMF has no lower effect than the exposure to ionizing radiation and should not be underestimated.