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Autosomal dominant polycystic kidney disease and pericardial effusion
Joint Authors
Fernandez, Guillermo Alberto Perez
Ismail, Muntasir Y.
Source
Issue
Vol. 33, Issue 5 (30 Sep. 2018), pp.429-432, 4 p.
Publisher
Publication Date
2018-09-30
Country of Publication
Oman
No. of Pages
4
Main Subjects
Abstract EN
The autosomal dominant polycystic kidney disease (ADPKD) accounts for one out of 400–1000 live births, being a hereditary disorder with cystic and noncystic manifestations as well as extrarenal involvement.
The pericardial effusion (PE) in the context of a patient with ADPKD is complex, and it is not entirely defined.
Several theories have been proposed.
The most accepted, so far, is linked to mutations in the PKD1 gene which can entail an abnormal production of matrix components, matrixdegrading enzymes, and inhibitors of metalloproteinases, and defects in connective tissue which would lead to an abnormal distensibility of the connective tissue.
We report the case of a 35-year-old female Moroccan patient with the diagnosis of ADPKD associated with arterial hypertension who came into the Emergency Department with lower abdominal pain lasting for five days being diagnosed as salpingitis.
Abdominal computed tomography scan with contrast showed both kidneys with several cystic images with a thin wall.
A transthoracic echocardiogram revealed the presence of moderate PE more in the anterior aspect.
A greater set of standard tests to rule out collagen vascular disease, rheumatoid diseases, autoimmune disorders, and malignancies was ordered.
These tests yielded no abnormality.
The association of ADPKD with PE is rare.
The awareness of this connection by the emergency physicians is key to prevent misplaced concern.
American Psychological Association (APA)
Fernandez, Guillermo Alberto Perez& Ismail, Muntasir Y.. 2018. Autosomal dominant polycystic kidney disease and pericardial effusion. Oman Medical Journal،Vol. 33, no. 5, pp.429-432.
https://search.emarefa.net/detail/BIM-903860
Modern Language Association (MLA)
Fernandez, Guillermo Alberto Perez& Ismail, Muntasir Y.. Autosomal dominant polycystic kidney disease and pericardial effusion. Oman Medical Journal Vol. 33, no. 5 (Sep. 2018), pp.429-432.
https://search.emarefa.net/detail/BIM-903860
American Medical Association (AMA)
Fernandez, Guillermo Alberto Perez& Ismail, Muntasir Y.. Autosomal dominant polycystic kidney disease and pericardial effusion. Oman Medical Journal. 2018. Vol. 33, no. 5, pp.429-432.
https://search.emarefa.net/detail/BIM-903860
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references : p. 431-432
Record ID
BIM-903860