The effects of dried amniotic membrane on epithelialization in secondary wound healing : an experimental study
Joint Authors
Muhammad, Zaid A.
Rajab, Ata Allah Fathi
Source
Issue
Vol. 16, Issue 1 (31 Dec. 2016), pp.49-58, 10 p.
Publisher
University of Mosul College of Dentistry
Publication Date
2016-12-31
Country of Publication
Iraq
No. of Pages
10
Main Subjects
Abstract EN
To investigate the efficacy of dried gamma-irradiated amniotic membrane dressing for the healing of full-thickness skin wounds, using a rabbit model.
Materials and Methods: This study was performed in the Oral and Maxillofacial sugery Department, College of Dentistry, University of Mosul, Iraq.
Twenty, locally bred, six to eight months old male rabbits were planned to conduct the study.
Bilateral full-thickness circular segments approximately 10 mm in diameter and nearly (3-4)mm in thickness were excised from the the back of each rabbit ( near to the mid-dorsum area) with a surgical blade; one dorsal skin wounding was performed lateral to the midline on right side, the other wound was performed lateral to the midline on left side.
The right wound was used as an experimental wound and covered with dried amniotic membrane whereas the left wound was considered as a control wound.
All wounds were covered with non adherent moist occlusive gauze.
Animals were divided into four groups according to sacrificing date ( 3, 7, 14, 30) days.
Skin specimens were collected after sacrificing the rabbits.
The specimens were placed in formalde-hyde and sent for histopathological examination and scoring for wound healing.
Results: The histopatho-logical findings of this study revealed that there was a significant difference of reepithelialization between the two groups at two weeks period, at p-value < 0.05, while there was no significant difference at 3 days, one week, and one month.
Conclusions: This study concluded that amniotic membrane can be used as a safe dressing, promoting epithelialization on secondary wounds.
American Psychological Association (APA)
Muhammad, Zaid A.& Rajab, Ata Allah Fathi. 2016. The effects of dried amniotic membrane on epithelialization in secondary wound healing : an experimental study. al-Rafidain Dental Journal،Vol. 16, no. 1, pp.49-58.
https://search.emarefa.net/detail/BIM-903886
Modern Language Association (MLA)
Muhammad, Zaid A.& Rajab, Ata Allah Fathi. The effects of dried amniotic membrane on epithelialization in secondary wound healing : an experimental study. al-Rafidain Dental Journal Vol. 16, no. 1 (2016), pp.49-58.
https://search.emarefa.net/detail/BIM-903886
American Medical Association (AMA)
Muhammad, Zaid A.& Rajab, Ata Allah Fathi. The effects of dried amniotic membrane on epithelialization in secondary wound healing : an experimental study. al-Rafidain Dental Journal. 2016. Vol. 16, no. 1, pp.49-58.
https://search.emarefa.net/detail/BIM-903886
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references : p. 56-58
Record ID
BIM-903886