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Effect of azithromycin in treatment of cutaneous leishmaniasis
Other Title(s)
تأثير ازثرومايسين في علاج عدوى ليشمانيا الجلدية (حبة بغداد)
Author
Source
The Medical Journal of Basrah University
Issue
Vol. 36, Issue 2 (31 Dec. 2018), pp.113-118, 6 p.
Publisher
University of Basrah College of Medicine
Publication Date
2018-12-31
Country of Publication
Iraq
No. of Pages
6
Main Subjects
Abstract EN
Introduction: Leishmaniasis is a vector born protozoal infection.
Cutaneous leishmaniasis outbreak occurred during 2014 in Erbil governorate, Kurdistan-Iraq.
First choice of its treatment is pentavalent antimony.
Other options of treatment are available.
Azithromycin is used as trial to be effective but human studies are lacking.
Patients and Methods: Prospective randomized open labeled interventional study conducted on 63 patients.
The sample divided in to two groups.
Group A received only intra-lesional sodium stibogluconate and the group B received combination therapy of intra-lesional sodium stibogluconate and azithromycin 500 mg orally.
Follow up done for lesions’ healing at 6th week and at the end of 8th week of therapy.
Results: Nodular lesions were dominant morphology among the Lesions (71.5%).
Lesions mostly were ulcerated (59%).
Mean duration of lesions were 3 ± 1.1 and 2.4 ± 1.8 weeks in patients of group A and B respectively.
At 6th week in patients of group A, there were 13(41.9%) patients with complete healing of the lesions, while in group B it was found in 23(71.8%) patients.
At the end of 8th week group A patients showed complete healing in 21(67.7%) patients while in patients of group B complete healing found in 27(84.3%).
Conclusions: Results of this study concludes that combination therapy of azithromycin and intra-lesional sodium stibogluconate provides more therapeutic effect if compared with the effect of intra-lesional sodium stibogluconate alone
American Psychological Association (APA)
Qurtas, Dindar Sharif. 2018. Effect of azithromycin in treatment of cutaneous leishmaniasis. The Medical Journal of Basrah University،Vol. 36, no. 2, pp.113-118.
https://search.emarefa.net/detail/BIM-904186
Modern Language Association (MLA)
Qurtas, Dindar Sharif. Effect of azithromycin in treatment of cutaneous leishmaniasis. The Medical Journal of Basrah University Vol. 36, no. 2 (2018), pp.113-118.
https://search.emarefa.net/detail/BIM-904186
American Medical Association (AMA)
Qurtas, Dindar Sharif. Effect of azithromycin in treatment of cutaneous leishmaniasis. The Medical Journal of Basrah University. 2018. Vol. 36, no. 2, pp.113-118.
https://search.emarefa.net/detail/BIM-904186
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references : p. 118
Record ID
BIM-904186