Neuroprotective and therapeutic effect of Cordyceps militaris on ischemia-induced neuronal death and cognitive impairments
Joint Authors
Kim, Young Ock
Kim, Hak Jae
Oh, Junsang
Abu al-Tawil, Jasim Muhammad
Sung, Gi Ho
Source
Saudi Journal of Biological Sciences
Issue
Vol. 26, Issue 7 (30 Nov. 2019), pp.1352-1357, 6 p.
Publisher
Publication Date
2019-11-30
Country of Publication
Saudi Arabia
No. of Pages
6
Main Subjects
Topics
Abstract EN
Cordyceps militaris is a type of fungus consumed by people all over the world and renowned for their nutritional benefits and herbal formulas to promote health and longevity.
In the present study investigation was carried out to explore the therapeutic properties and neuroprotective effect of the C.
militaris on ischemic brain neuronal injury, impairment of memory and learning in experimental rats induced by a global cerebral ischemia-reperfusion injury in WISTAR rats.
Vascular Dementia with transient global brain injuries induced by a four-vessel occlusion (4-VO) in WISTAR rats.
Further, donepezil (5 mg/kg) and C.
militaris was (100 and 300 mg/kg, p.o.) were orally administered for 7 days in 4-VO WISTAR rats.
C.
militaris has the ability to improve memory impairments due to global cerebral ischemia and scopolamine-induced memory deterioration.
Our present findings suggest that C.
militaris may be a potential candidate for the neuroprotection of hippocampus and the recovery of various vascular dementia or neuroinflammatory disorders.
American Psychological Association (APA)
Kim, Young Ock& Kim, Hak Jae& Abu al-Tawil, Jasim Muhammad& Oh, Junsang& Sung, Gi Ho. 2019. Neuroprotective and therapeutic effect of Cordyceps militaris on ischemia-induced neuronal death and cognitive impairments. Saudi Journal of Biological Sciences،Vol. 26, no. 7, pp.1352-1357.
https://search.emarefa.net/detail/BIM-909980
Modern Language Association (MLA)
Kim, Young Ock…[et al.]. Neuroprotective and therapeutic effect of Cordyceps militaris on ischemia-induced neuronal death and cognitive impairments. Saudi Journal of Biological Sciences Vol. 26, no. 7 (Nov. 2019), pp.1352-1357.
https://search.emarefa.net/detail/BIM-909980
American Medical Association (AMA)
Kim, Young Ock& Kim, Hak Jae& Abu al-Tawil, Jasim Muhammad& Oh, Junsang& Sung, Gi Ho. Neuroprotective and therapeutic effect of Cordyceps militaris on ischemia-induced neuronal death and cognitive impairments. Saudi Journal of Biological Sciences. 2019. Vol. 26, no. 7, pp.1352-1357.
https://search.emarefa.net/detail/BIM-909980
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references : p. 1356-1357
Record ID
BIM-909980