Cellular proliferationcytotoxicity and antimicrobial potentials of green synthesized silver nanoparticles (AgNPs) using Juniperus procera
Joint Authors
al-Islam, Sayf
Ghramh, Hamid Ali
Kilani, Muna
Ibrahim, Isam H.
Khan, Khalid Ali
Source
Saudi Journal of Biological Sciences
Issue
Vol. 26, Issue 7 (30 Nov. 2019), pp.1689-1694, 6 p.
Publisher
Publication Date
2019-11-30
Country of Publication
Saudi Arabia
No. of Pages
6
Main Subjects
Topics
Abstract EN
Juniperus spp.
are used as medicinal plants in many countries like Bosnia, Lebanon, and Turkey.
In folk medicines, these plants have been used for treating skin and respiratory tract diseases, urinary problems, rheumatism and gall bladder stones.
The objectives of this work were to synthesize silver nanoparticles (AgNPs) using a coniferous tree, Juniperus procera leaf extract and testing the synthesized AgNPs for its antimicrobial potentials, hemolytic activity, toxicity and the proliferative effects against normal and activated rat splenic cells.
Leaf extract was prepared using acetone and ethanol as solvents.
AgNPs were prepared using the acetone extract.
AgNPs were validated using UV–Vis spectroscopy and scanning electron microscopy (SEM).
Functional groups in the extract were identified using Fourier Transform Infrared (FT-IR) spectroscopy.
SEM images of AgNPs showed spherical and cubic shapes with a uniform size distribution with an average size of 30–90 nm.
FT-IR spectroscopy showed the presence of many functional groups in the plant extract.
AgNPs showed promising antimicrobial activity against tested bacteria and fungus.
AgNPs also expressed a stimulating activity towards the rat splenic cells in a dose dependent manner.
Acetone as solvent was safer on cells than ethanol.
Green synthesized AgNPs using J.
procera might be used as a broad-spectrum therapeutic agent against microorganisms and as an immunostimulant agent.
American Psychological Association (APA)
Ibrahim, Isam H.& Kilani, Muna& Ghramh, Hamid Ali& Khan, Khalid Ali& al-Islam, Sayf. 2019. Cellular proliferationcytotoxicity and antimicrobial potentials of green synthesized silver nanoparticles (AgNPs) using Juniperus procera. Saudi Journal of Biological Sciences،Vol. 26, no. 7, pp.1689-1694.
https://search.emarefa.net/detail/BIM-910295
Modern Language Association (MLA)
Ibrahim, Isam H.…[et al.]. Cellular proliferationcytotoxicity and antimicrobial potentials of green synthesized silver nanoparticles (AgNPs) using Juniperus procera. Saudi Journal of Biological Sciences Vol. 26, no. 7 (Nov. 2019), pp.1689-1694.
https://search.emarefa.net/detail/BIM-910295
American Medical Association (AMA)
Ibrahim, Isam H.& Kilani, Muna& Ghramh, Hamid Ali& Khan, Khalid Ali& al-Islam, Sayf. Cellular proliferationcytotoxicity and antimicrobial potentials of green synthesized silver nanoparticles (AgNPs) using Juniperus procera. Saudi Journal of Biological Sciences. 2019. Vol. 26, no. 7, pp.1689-1694.
https://search.emarefa.net/detail/BIM-910295
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references : p. 1693-1694
Record ID
BIM-910295