Development of response surface methodology for optimization of parameters and quantitative analysis of chebulinic acid from composition of medicinal herbs by HPLC
Joint Authors
Munawar, T. Mohammad
Prakash, D. V. Surya
Vangalapati, Meena
Source
Saudi Journal of Biological Sciences
Issue
Vol. 26, Issue 7 (30 Nov. 2019), pp.1809-1814, 6 p.
Publisher
Publication Date
2019-11-30
Country of Publication
Saudi Arabia
No. of Pages
6
Main Subjects
Topics
- Methodology
- Medicinal plants
- Biological response modifiers
- Liquid chromatography
- Response surfaces(Statistics)
Abstract EN
The purpose of the research is to study the development of response surface methodology for optimization of chebulinic acid extraction from composition of medicinal herbs such as Terminalia chebula, Phyllanthus emblica and seeds of Dimocarpus longan.
Optimization of extraction parameters such as weight dosages, pH and time were carried out by response surface methodology (RSM).
The optimal conditions determined for extraction of chebulinic acid through response surface methodology were dosage (6.25 g), pH (5.7) and time (24.23 h).
These results showed that the developed model is satisfactory and relevant for the extraction of chebulinic acid.
The analysis of variance showed a high goodness of model fit and the performance of the RSM method for improving chebulinic acid extraction from the composition of medicinal herbs.
Quantitative estimation of chebulinic acid in the composition of medicinal herbs by HPLC studies revealed that 0.712% w/w of chebulinic acid content was present in the composition of herbal powder.
American Psychological Association (APA)
Munawar, T. Mohammad& Prakash, D. V. Surya& Vangalapati, Meena. 2019. Development of response surface methodology for optimization of parameters and quantitative analysis of chebulinic acid from composition of medicinal herbs by HPLC. Saudi Journal of Biological Sciences،Vol. 26, no. 7, pp.1809-1814.
https://search.emarefa.net/detail/BIM-910426
Modern Language Association (MLA)
Munawar, T. Mohammad…[et al.]. Development of response surface methodology for optimization of parameters and quantitative analysis of chebulinic acid from composition of medicinal herbs by HPLC. Saudi Journal of Biological Sciences Vol. 26, no. 7 (Nov. 2019), pp.1809-1814.
https://search.emarefa.net/detail/BIM-910426
American Medical Association (AMA)
Munawar, T. Mohammad& Prakash, D. V. Surya& Vangalapati, Meena. Development of response surface methodology for optimization of parameters and quantitative analysis of chebulinic acid from composition of medicinal herbs by HPLC. Saudi Journal of Biological Sciences. 2019. Vol. 26, no. 7, pp.1809-1814.
https://search.emarefa.net/detail/BIM-910426
Data Type
Journal Articles
Language
English
Record ID
BIM-910426