Reverse relationship of uric acid and vitamin D3 in adult patients with rheumatoid arthritis and systemic lupus erythematosus
Joint Authors
Diyab, Diyab al-Tayyib
Hasan, Adlah Bakri
Madani, Shayma
Farid, Iman
Source
Issue
Vol. 41, Issue 4 (31 Dec. 2019), pp.246-250, 5 p.
Publisher
King Hamad University Hospital
Publication Date
2019-12-31
Country of Publication
Bahrain
No. of Pages
5
Main Subjects
Topics
Abstract EN
Background: The relationship between uric acid (UA) and vitamin D3 (25(OH)D) in rheumatoid arthritis (RA) and systemic lupus erythematosus (SLE) patients has not been settled yet.
Objective: To evaluate a possible link between UA and 25(OH)D serum levels and vitamin D3 therapy in patients with RA compared to SLE.
Design: A Retrospective Study.
Setting: Salmaniya Medical Complex, Ministry of Health, Bahrain.
Method: Eighty patients with RA and SLE from March 2015 to September 2018 were included in the study.
Serum level of UA and 25(OH) D levels were estimated before and after oral vitamin D3 therapy.
Data were analyzed using SPSS version 19.
Result: RA and SLE had a significant increase in mean serum 25(OH)D, (P=0.0001) after vitamin D3 therapy, but a decreased mean serum UA (P=0.0001).
The increase in 25(OH)D was more prominent in SLE (P=0.0001) compared to RA (P=0.002), while the decrease in serum UA after vitamin D3 therapy was more prominent in RA (P=0.0001) compared to SLE (P=0.048).
Conclusion: We found an inverse relation between serum 25(OH)D and UA in adult Bahraini patients with RA and SLE, which was more pronounced in RA compared to SLE patients.
American Psychological Association (APA)
Hasan, Adlah Bakri& Farid, Iman& Madani, Shayma& Diyab, Diyab al-Tayyib. 2019. Reverse relationship of uric acid and vitamin D3 in adult patients with rheumatoid arthritis and systemic lupus erythematosus. Bahrain Medical Bulletin،Vol. 41, no. 4, pp.246-250.
https://search.emarefa.net/detail/BIM-910499
Modern Language Association (MLA)
Hasan, Adlah Bakri…[et al.]. Reverse relationship of uric acid and vitamin D3 in adult patients with rheumatoid arthritis and systemic lupus erythematosus. Bahrain Medical Bulletin Vol. 41, no. 4 (Dec. 2019), pp.246-250.
https://search.emarefa.net/detail/BIM-910499
American Medical Association (AMA)
Hasan, Adlah Bakri& Farid, Iman& Madani, Shayma& Diyab, Diyab al-Tayyib. Reverse relationship of uric acid and vitamin D3 in adult patients with rheumatoid arthritis and systemic lupus erythematosus. Bahrain Medical Bulletin. 2019. Vol. 41, no. 4, pp.246-250.
https://search.emarefa.net/detail/BIM-910499
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references : p.249-250
Record ID
BIM-910499