Reverse relationship of uric acid and vitamin D3 in adult patients with rheumatoid arthritis and systemic lupus erythematosus

Joint Authors

Diyab, Diyab al-Tayyib
Hasan, Adlah Bakri
Madani, Shayma
Farid, Iman

Source

Bahrain Medical Bulletin

Issue

Vol. 41, Issue 4 (31 Dec. 2019), pp.246-250, 5 p.

Publisher

King Hamad University Hospital

Publication Date

2019-12-31

Country of Publication

Bahrain

No. of Pages

5

Main Topic

Medicine

Topics

Abstract EN

Background: The relationship between uric acid (UA) and vitamin D3 (25(OH)D) in rheumatoid arthritis (RA) and systemic lupus erythematosus (SLE) patients has not been settled yet.

Objective: To evaluate a possible link between UA and 25(OH)D serum levels and vitamin D3 therapy in patients with RA compared to SLE.

Design: A Retrospective Study.

Setting: Salmaniya Medical Complex, Ministry of Health, Bahrain.

Method: Eighty patients with RA and SLE from March 2015 to September 2018 were included in the study.

Serum level of UA and 25(OH) D levels were estimated before and after oral vitamin D3 therapy.

Data were analyzed using SPSS version 19.

Result: RA and SLE had a significant increase in mean serum 25(OH)D, (P=0.0001) after vitamin D3 therapy, but a decreased mean serum UA (P=0.0001).

The increase in 25(OH)D was more prominent in SLE (P=0.0001) compared to RA (P=0.002), while the decrease in serum UA after vitamin D3 therapy was more prominent in RA (P=0.0001) compared to SLE (P=0.048).

Conclusion: We found an inverse relation between serum 25(OH)D and UA in adult Bahraini patients with RA and SLE, which was more pronounced in RA compared to SLE patients.

American Psychological Association (APA)

Hasan, Adlah Bakri& Farid, Iman& Madani, Shayma& Diyab, Diyab al-Tayyib. 2019. Reverse relationship of uric acid and vitamin D3 in adult patients with rheumatoid arthritis and systemic lupus erythematosus. Bahrain Medical Bulletin،Vol. 41, no. 4, pp.246-250.
https://search.emarefa.net/detail/BIM-910499

Modern Language Association (MLA)

Hasan, Adlah Bakri…[et al.]. Reverse relationship of uric acid and vitamin D3 in adult patients with rheumatoid arthritis and systemic lupus erythematosus. Bahrain Medical Bulletin Vol. 41, no. 4 (Dec. 2019), pp.246-250.
https://search.emarefa.net/detail/BIM-910499

American Medical Association (AMA)

Hasan, Adlah Bakri& Farid, Iman& Madani, Shayma& Diyab, Diyab al-Tayyib. Reverse relationship of uric acid and vitamin D3 in adult patients with rheumatoid arthritis and systemic lupus erythematosus. Bahrain Medical Bulletin. 2019. Vol. 41, no. 4, pp.246-250.
https://search.emarefa.net/detail/BIM-910499

Data Type

Journal Articles

Language

English

Notes

Includes bibliographical references : p.249-250

Record ID

BIM-910499