Systemic vascular resistance guided vasopressor dose titration in a case of vasodilator shock caused by metformin
Joint Authors
Shirazi, Muhammad
Hakim, Karim
Chaari, Anis
Bousselmi, Kamil
Katus, Vipin
al-Jawdir, Shaykhah
Abd al-Aziz, Ala
Source
Issue
Vol. 41, Issue 4 (31 Dec. 2019), pp.260-262, 3 p.
Publisher
King Hamad University Hospital
Publication Date
2019-12-31
Country of Publication
Bahrain
No. of Pages
3
Main Subjects
Topics
- Calibration
- Drug efficacy
- Drugs
- Doses drugs
- Blood pressure
- Hypotensive agents
- Type 2 diabetes
- Cardiogenic shock
Abstract EN
Vasodilator shock and metformin-associated lactic acidosis (MALA) are the worst adverse effects of metformin toxicity.
Systemic vascular resistance (SVR) is known to be decreased in vasodilator shock.
Accordingly, vasopressors are the treatment of choice of vasodilator shock; their effect is via increasing the SVR.
Cardiac output can be measured accurately and non-invasively using transthoracic echocardiography (TTE).
A fifty-seven-year-old male patient was admitted with vasodilator shock induced by metformin toxicity.
TTE was used to provide serial measurements of the SVR.
Accordingly, vasopressor doses were titrated.
The patient received vasopressor therapy, standard supportive medical treatment, in addition to continuous renal replacement therapy.
On the sixth ICU day, epinephrine was weaned off, followed by nor-epinephrine on the tenth day.
The patient was transferred to the ward by the fifteenth day.
American Psychological Association (APA)
Shirazi, Muhammad& Hakim, Karim& Chaari, Anis& Bousselmi, Kamil& Katus, Vipin& Abd al-Aziz, Ala…[et al.]. 2019. Systemic vascular resistance guided vasopressor dose titration in a case of vasodilator shock caused by metformin. Bahrain Medical Bulletin،Vol. 41, no. 4, pp.260-262.
https://search.emarefa.net/detail/BIM-910501
Modern Language Association (MLA)
Shirazi, Muhammad…[et al.]. Systemic vascular resistance guided vasopressor dose titration in a case of vasodilator shock caused by metformin. Bahrain Medical Bulletin Vol. 41, no. 4 (Dec. 2019), pp.260-262.
https://search.emarefa.net/detail/BIM-910501
American Medical Association (AMA)
Shirazi, Muhammad& Hakim, Karim& Chaari, Anis& Bousselmi, Kamil& Katus, Vipin& Abd al-Aziz, Ala…[et al.]. Systemic vascular resistance guided vasopressor dose titration in a case of vasodilator shock caused by metformin. Bahrain Medical Bulletin. 2019. Vol. 41, no. 4, pp.260-262.
https://search.emarefa.net/detail/BIM-910501
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references : p. 262
Record ID
BIM-910501