Evaluation of some clotting factors (FI, FVII, FVIII and FIX) and estradiol hormone deficiency in menopausal women
Author
al-Sadi, Rim Abd al-Rahim Mardan
Source
مجلة جامعة الكوفة لعلوم الحياة : مجلة علمية محكمة
Publisher
University of Kufa Faculty of Science Department of live Sciences
Publication Date
2018-12-31
Country of Publication
Iraq
No. of Pages
7
Main Subjects
Topics
English Abstract
Women are complained from several physiological and biochemical disturbances when they become aged and loss adequate amount of estradiol hormone secreted from ovarian follicles .
The present study conduct to evaluate the concentration of some available clotting factors and feminizing hormone ( estradiol hormone) in menopausal women .
A total number of participants postmenopausal women was sixty (60) women and their ages were 50 to 69 years old and fifteen (15) women their ages premenopausal women ( control group) that they have normal menstruation cycle and whose ages ranged between 20 – 25 years old.
The aging women ( menopause ) were subdivided according to their ages periods in to four groups , the first group ( 50 – 54 years ) , second group ( 55 – 59years ) , third group ( 60- 64 years) , and fourth group (65 –69 years ).
Values of estradiol hormone recorded a significant drop in all groups of postmenopausal women in matching with counter parts of premenopausal women .
About prothrombin time (PT) , its results showed a remarkable elevation ( p<0.05 ) in all groups of menopausal women when compared with control group .
Values of intrinsic pathway test ( activated partial thromboplastin time ) indicated remarkable increase (p<0.05 ) in all tested groups( menopausal women) compared to control group .In regard to clotting factors , levels of fibrinogen (FI) concentrations did significantly progressive elevated (p<0.05) in all postmenopausal women groups in matching with those of control group .
Also, concentrations of stable factor (VII) were significantly increased ( p<0.05) , whereas antihemophilic factors (VIII) and Christmas factor ( IX ) pointed out a significant progressive fall (p<0.05) of aging women in a comparison with premenopausal women.
In conclusion, deficiency of estradiol hormone in postmenopausal women appears associated with fluctuation of clotting factor concentrations and these disturbances can give an indicator that estradiol hormone maintain hemostatic mechanism to prevent risk of cardio- vascular problems.
Data Type
Conference Papers
Record ID
BIM-910881
American Psychological Association (APA)
al-Sadi, Rim Abd al-Rahim Mardan. 2018-12-31. Evaluation of some clotting factors (FI, FVII, FVIII and FIX) and estradiol hormone deficiency in menopausal women. International Scientific Conference (3rd : 2018 : Najaf, Iraq). . Special issue (2018), pp.78-84.Najaf Iraq : University of Kufa Faculty of Science Department of live Sciences.
https://search.emarefa.net/detail/BIM-910881
Modern Language Association (MLA)
al-Sadi, Rim Abd al-Rahim Mardan. Evaluation of some clotting factors (FI, FVII, FVIII and FIX) and estradiol hormone deficiency in menopausal women. . Najaf Iraq : University of Kufa Faculty of Science Department of live Sciences. 2018-12-31.
https://search.emarefa.net/detail/BIM-910881
American Medical Association (AMA)
al-Sadi, Rim Abd al-Rahim Mardan. Evaluation of some clotting factors (FI, FVII, FVIII and FIX) and estradiol hormone deficiency in menopausal women. . International Scientific Conference (3rd : 2018 : Najaf, Iraq).
https://search.emarefa.net/detail/BIM-910881