Hematological and biochemical effects of partial and complete splenectomy in dogs

Abstract EN

The purpose of the current study was to describe the effect of surgical splenectomy technique either partial or complete on some biochemical and hematological parameters.

Six male mature mongrel dogs were subdivided into two groups (complete and partial splenectomy), and six immature mongrel dogs were subdivided into two groups (complete and partial splenectomy).

Blood samples were taken before (base line), 10, 30, and 60 days post-operative.

The results showed a significant reduction in serum albumin and iron levels 10 days after partial and complete splenectomy in both immature and mature dogs.

However, serum gamma globulin fraction, ferritin, transferrin, and ceruloplasmin concentrations were significantly increased at the same period following surgical operation.

There was a perturbation in serum activity of transaminases, bilirubin, and urea levels.

The levels of WBCs, neutrophils, lymphocytes, MCH, MCHC, and platelets in completely splenectomized immature and mature dogs were increased.

While, the RBCs and Hb concentrations were significantly decreased following complete splenectomy in immature and mature dogs.

These results concluded that splenectomy in dogs may induce anemia, thrombosis, and inflammatory conditions but also increase cellular and humeral immunity as a compensatory mechanism.