Effect of administration of leptin on thyroid hormone in oxidative stress induced rats
Joint Authors
Madhkhur, Shayma Rabia
Ibrahim, Ihsan Raisan
Source
Journal of al-Qadisiyah for Pure Science
Issue
Vol. 23, Issue 1 (31 Mar. 2018), pp.1-6, 6 p.
Publisher
al-Qadisiyah University College of Science
Publication Date
2018-03-31
Country of Publication
Iraq
No. of Pages
6
Main Subjects
Abstract EN
The aim of this study was to investigate the relationship between exogenous leptin and thyroxin on some stress types in rats.
In this study 60 male wistar albino rats were divided into two main groups (first was 5 day, and second was 10 day), each one subdivided into six groups (5 rat per subgroup): Control And five treated groups ,which include: Leptin (10 μg/kg leptin, sc.
daily), oxidative stress (0.5% H2O2), leptin+ oxidative stress, Diabetes, (induced by single injection of streptoztocin (65 mg/kg bw)), and Leptin + diabetes.
At the end of the experiments the blood collected by cardiac puncture under anesthesia.
Plasma thyroxin and corticosterone were measured.
Our results showed that stress decreases thyroxin level and increases corticosterone level, while leptin treatment reverse these changes.
American Psychological Association (APA)
Madhkhur, Shayma Rabia& Ibrahim, Ihsan Raisan. 2018. Effect of administration of leptin on thyroid hormone in oxidative stress induced rats. Journal of al-Qadisiyah for Pure Science،Vol. 23, no. 1, pp.1-6.
https://search.emarefa.net/detail/BIM-913759
Modern Language Association (MLA)
Madhkhur, Shayma Rabia& Ibrahim, Ihsan Raisan. Effect of administration of leptin on thyroid hormone in oxidative stress induced rats. Journal of al-Qadisiyah for Pure Science Vol. 23, no. 1 (2018), pp.1-6.
https://search.emarefa.net/detail/BIM-913759
American Medical Association (AMA)
Madhkhur, Shayma Rabia& Ibrahim, Ihsan Raisan. Effect of administration of leptin on thyroid hormone in oxidative stress induced rats. Journal of al-Qadisiyah for Pure Science. 2018. Vol. 23, no. 1, pp.1-6.
https://search.emarefa.net/detail/BIM-913759
Data Type
Journal Articles
Language
English
Notes
Record ID
BIM-913759