Synthesis and characterization of some N-arylhydrazone and Imides derivatives from nalidixic acid

Abstract EN

This research comprises the synthesizes of N-Arylhydrazone and Imides derivatives of Nalidixic acid were prepared by esterification of Nalidixic acid to form compound (1) then reacted with hydrazine hydrate 99% in ethanol to yield hydrazide derivative compound (2).

The Schiff base (3a-3c) prepared from the corresponding aryl aldehydes with compound (2).

Imides derivatives (4-6) were synthesized by reaction of compound (2) with appropriate anhydrides .The structures of compounds have been characterized by using some spectroscopic methods, 1HNMR and FT-IR.