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Analysis of bioactive composites and antiviral activity of Iresine herbstii extracts against Newcastle disease virus in ovo
Joint Authors
al-Ghanim, K. A.
Mahbub, Shahid
al-Misnid, Fahd Abd Allah
Ashraf, Asma Tahir
Asad, Farkhanda
Ali, Tibah
Muzammil, Saimah
Naz, Shabanah
Rafi, Rida
Ahmad, Zubayr
Source
Saudi Journal of Biological Sciences
Issue
Vol. 27, Issue 1 (31 Jan. 2020), pp.335-340, 6 p.
Publisher
Publication Date
2020-01-31
Country of Publication
Saudi Arabia
No. of Pages
6
Main Subjects
Topics
Abstract EN
The study was implemented to actuate the qualitative and quantitative phyto constituents of Iresine herbstii extracts and its antiviral efficacy against avian ND virus.
Among four tested solvents, the ethanolic extract of Iresine herbstii revealed the presence of highest quantity of all tested phytochemicals while petroleum ether extract showed the least.
Folin-Ciocalteu method assessed the range of TPC extended from 81.01 ± 0.67 to 126.35 ± 0.45 µg GAE/mg.
Acetonic extract showed the highest amount among all extracts and petroleum ether possessed the lower quantity.
TFC ranged from 54.37 ± 0.45 to 88.12 ± 0.26 µg QE/mg followed by colorimetric method.
From all extract ethanolic extract showed highest quantity and petroleum ether revealed the lower.
HPLC analysis of ethanolic extract of I.
herbstii confesses the presence six bioactive components by using the HP5-MS column.
To check the antiviral potential of plants, different prepared treatments of plant extract and live virus were inoculated at 9 days old SPF embryonated chicken eggs.
Results exposed that all plant extracts produce antiviral activity against NDV in ovo according to their potential and phytochemical profile.
The highest survival rate was observed in the ethanolic extract at 400 µg/mL and acetonic extract at 300 µg/mL as it controls the NDV activity completely, evidence of absence of embryo death and HA titre.
Dichloromethane and petroleum ether could not inhibit the virus completely.
600 µg/mL concentration was proved as toxic in all extracts except petroleum ether extract which showed a dose dependent pattern.
American Psychological Association (APA)
Andleeb, Rahat& Ashraf, Asma Tahir& Muzammil, Saimah& Naz, Shabanah& Asad, Farkhanda& Ali, Tibah…[et al.]. 2020. Analysis of bioactive composites and antiviral activity of Iresine herbstii extracts against Newcastle disease virus in ovo. Saudi Journal of Biological Sciences،Vol. 27, no. 1, pp.335-340.
https://search.emarefa.net/detail/BIM-920656
Modern Language Association (MLA)
Andleeb, Rahat…[et al.]. Analysis of bioactive composites and antiviral activity of Iresine herbstii extracts against Newcastle disease virus in ovo. Saudi Journal of Biological Sciences Vol. 27, no. 1 (Jan. 2020), pp.335-340.
https://search.emarefa.net/detail/BIM-920656
American Medical Association (AMA)
Andleeb, Rahat& Ashraf, Asma Tahir& Muzammil, Saimah& Naz, Shabanah& Asad, Farkhanda& Ali, Tibah…[et al.]. Analysis of bioactive composites and antiviral activity of Iresine herbstii extracts against Newcastle disease virus in ovo. Saudi Journal of Biological Sciences. 2020. Vol. 27, no. 1, pp.335-340.
https://search.emarefa.net/detail/BIM-920656
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references : p. 340
Record ID
BIM-920656