The activity of extracts chara vulgaris against promastigotes of leishmania tropica
Other Title(s)
فعالية مستخلصات طحلب الكارا ضد الطور المسوط للشمانيا المدارية الجلدية
Parallel Title
فعالية مستخلصات طحلب الكارا ضد الطور المسوط للشمانيا المدارية الجلدية
Joint Authors
Ali, Ban Husayn
al-Halbusi, Muhammad Mahmud Farhan
Salih, Thair Abd al-Qadir
Source
Journal of Biotechnology Research Center
Issue
Vol. 12, Issue 2 (31 Dec. 2018), pp.66-72, 7 p.
Publisher
al-Nahrain University Biotechnology Research Center
Publication Date
2018-12-31
Country of Publication
Iraq
No. of Pages
7
Main Subjects
Abstract EN
Leishmaniasis is a widespread parasitic disease caused by Leishmania parasite, this disease considers as a major health problem worldwide.
The available therapy is unsatisfactory expensive with a cytotoxic side effects.
Studies of marine algae as a source of pharmacological active compounds have increased worldwide.
This study was aimed to investigate the effect of a type of green algae (Chara vulgaris) on promastigotes of L.
tropica, by using.
various concentrations (500, 250, 125, 62.5, 31.25, 15.6 μg/mL) in vitro by MTT assay [3-(4.5-dimethylthiazol-2-yl)- 2.5-diphenyl tetrazolium bromide)], to investigate its effect on the proliferation of promastigotes, by three incubation periods (24, 48, 72 hr.) The results showed a significant (p< 0.05) decrease in survived of promastigotes in treatment groups with concentrations that ranged between 15 to 500 μg/ ml.
This study revealed a major growth inhibition effect of the organic extract of C.
vulgaris against L.
tropica promastigotes, and the extract of ethyl acetate showed potential activity is better than the aqueous extract.
American Psychological Association (APA)
Ali, Ban Husayn& Salih, Thair Abd al-Qadir& al-Halbusi, Muhammad Mahmud Farhan. 2018. The activity of extracts chara vulgaris against promastigotes of leishmania tropica. Journal of Biotechnology Research Center،Vol. 12, no. 2, pp.66-72.
https://search.emarefa.net/detail/BIM-920987
Modern Language Association (MLA)
Ali, Ban Husayn…[et al.]. The activity of extracts chara vulgaris against promastigotes of leishmania tropica. Journal of Biotechnology Research Center Vol. 12, no. 2 (2018), pp.66-72.
https://search.emarefa.net/detail/BIM-920987
American Medical Association (AMA)
Ali, Ban Husayn& Salih, Thair Abd al-Qadir& al-Halbusi, Muhammad Mahmud Farhan. The activity of extracts chara vulgaris against promastigotes of leishmania tropica. Journal of Biotechnology Research Center. 2018. Vol. 12, no. 2, pp.66-72.
https://search.emarefa.net/detail/BIM-920987
Data Type
Journal Articles
Language
English
Notes
Record ID
BIM-920987