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Ovarian response of immature Syrian female hamster treated with different doses of hMG
Other Title(s)
الاستجابة المبيضية لإناث الهامستر السوري الفتية المعاملة بجرعات مختلفة من hMG
Author
Source
Damascus University Journal for the Agricultural Sciences
Issue
Vol. 34, Issue 2 (31 Dec. 2018), pp.9-18, 10 p.
Publisher
Publication Date
2018-12-31
Country of Publication
Syria
No. of Pages
10
Main Subjects
Abstract EN
Human menopausal gonadotropin (hMG) is commonly used in human assisted reproduction.
However, effects of hMG on follicular development remain controversial, due to its high LH- content.
The present study aimed to elucidate the relationship between the dosage of injected hMG and the ovarian response of immature Syrian hamsters.
Three groups of immature Syrian female hamster (n=10) were administrated intraperitoneally with 5, 10 or 15 IU of hMG, respectively.
As a control group, 10 cyclic females were permitted coitus with males of proven fertility and allowed to deliver pups.
Ovaries were collected at 2 d after hCG administration, and all follicles and corpora lutea were counted under a stereomicroscope.
The hMG administration induced significant (P< 0.05) and distinct morphological changes in the ovaries, as it promoted the follicular development with a dose – dependent manner.
The mean number of follicles was 29.2, 40.6 and 42.2, respectively, as compared to a mean of 9.6 follicles in the control group.
However, a reduced ovulation rate was recorded as only 1.7, 10.4 and 16 corpora lutea were found in the ovaries.
Overall, the present findings suggest that hMG, while suitable for inducing multiple follicular development in Syrian hamster, affected negatively on ovulation rates, thus, is largely ineffective for producing multiple embryos suitable for transfer.
American Psychological Association (APA)
Salih, Muhammad. 2018. Ovarian response of immature Syrian female hamster treated with different doses of hMG. Damascus University Journal for the Agricultural Sciences،Vol. 34, no. 2, pp.9-18.
https://search.emarefa.net/detail/BIM-925300
Modern Language Association (MLA)
Salih, Muhammad. Ovarian response of immature Syrian female hamster treated with different doses of hMG. Damascus University Journal for the Agricultural Sciences Vol. 34, no. 2 (2018), pp.9-18.
https://search.emarefa.net/detail/BIM-925300
American Medical Association (AMA)
Salih, Muhammad. Ovarian response of immature Syrian female hamster treated with different doses of hMG. Damascus University Journal for the Agricultural Sciences. 2018. Vol. 34, no. 2, pp.9-18.
https://search.emarefa.net/detail/BIM-925300
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references : p. 17-18
Record ID
BIM-925300