Protective effects of red palm oil and super red palm olein on hypercholesterolemic rats
Other Title(s)
التأثيرات الوقائية لزيت النخيل الأحمر و سوبر أولين النخيل الأحمر على الفئران المصابة بارتفاع مستوى الكوليسترول
Joint Authors
Yasin, Nisrin Muhammad Nabih
Muhammad, Huda Hasan Ibrahim
Allam, Majidah Habib
Hafiz, Saib Abd al-Munim
Source
Arab Universities Journal of Agricultural Sciences
Issue
Vol. 26, Issue 2 C (31 Dec. 2018), pp.1931-1942, 12 p.
Publisher
Ain Shams University Faculty of Agriculture
Publication Date
2018-12-31
Country of Publication
Egypt
No. of Pages
12
Main Subjects
Topics
Abstract EN
The present work was conducted to study the effect of red palm oil (RPO) and super red palm olien (SRPOL) on the nutritional parameters of rats suffering from hypercholesterolemic.
The vitamins (E, A, D and K) and β carotene were determinate by HPLC and indicated that RPO and SRPOL are considered the richest vegetable oils of antioxidant specially α- tocopherol and β carotene.
Thirty male rats weighting approximately 210 grams were di-vided into five groups, each group containing six rats.
Group G1 fed on basal diet as a control nega-tive group.
Group G2 fed on basal diets containing 2% of cholesterol as a control positive group and the other groups G3, G4 and G5 fed on the same diet used in group G2, yet the corn oil was re-placed by RPO in G3 and SRPOL in G4, Mean-while, group G5 was fed on the same diet used in group G2 and supplemented with a drug contained Lipitor Atorvastatin (20 mg/Kg BW rat daily by stomach tube).
Concerning biological evaluation all the studied dietary oils compared to positive con-trol group caused an decreases in serum LDL-c and TC and significantly increased HDL-c over the feeding period of experimental rat groups, thereby decreased the TC/HDL-c and LDL-c/HDL-c ratios.
Aspartate transaminase (AST), alanine transami-nase (ALT) enzymes and albumin in rats serum were generally decreased by RPO, SRPOL and drug Lipitor compared to positive control group.
Also urea, creatnine and uric acid levels in rats serum were significantly decreased by the studied oils and drug.
However, a significant increment in the activities of glutathione peroxidase (GPXs), catalase and total antioxidant were observed in blood of hypercholesterolemic rats treated with RPO, SRPOL and drug.
As such, the treated groups showed a significant decrement in malondialdehyde (MDA) in plasma.
American Psychological Association (APA)
Muhammad, Huda Hasan Ibrahim& Allam, Majidah Habib& Yasin, Nisrin Muhammad Nabih& Hafiz, Saib Abd al-Munim. 2018. Protective effects of red palm oil and super red palm olein on hypercholesterolemic rats. Arab Universities Journal of Agricultural Sciences،Vol. 26, no. 2 C, pp.1931-1942.
https://search.emarefa.net/detail/BIM-929633
Modern Language Association (MLA)
Muhammad, Huda Hasan Ibrahim…[et al.]. Protective effects of red palm oil and super red palm olein on hypercholesterolemic rats. Arab Universities Journal of Agricultural Sciences Vol. 26, no. 2 C (2018), pp.1931-1942.
https://search.emarefa.net/detail/BIM-929633
American Medical Association (AMA)
Muhammad, Huda Hasan Ibrahim& Allam, Majidah Habib& Yasin, Nisrin Muhammad Nabih& Hafiz, Saib Abd al-Munim. Protective effects of red palm oil and super red palm olein on hypercholesterolemic rats. Arab Universities Journal of Agricultural Sciences. 2018. Vol. 26, no. 2 C, pp.1931-1942.
https://search.emarefa.net/detail/BIM-929633
Data Type
Journal Articles
Language
English
Notes
Record ID
BIM-929633