تقييم فعالية مادّة كربونات الكالسيوم المشتقة من قشرة البيض كمادة تطعيم عظمي عند الأرانب

Abstract EN

Background and Objective: this study aimed to evaluate the efficiency of calcium carbonate (CaCo3) derived from Hen’s eggshells in repairing induced bony defects in the rabbit’s jaws bones; this material is always available in low cost and easy preparation.

Materials and Methods: the study was conducted on 20 male adult rabbits; three bony defects were induced in the lower and upper jaws.

Grafting materials were prepared as following: 1- material(A): calcium carbonate derived from eggshell was mixed with bone morphogenic protein BMP7; 2- material (B) : calcium carbonate derived from eggshell in the form of powder; the third defect was left as a control.

Animals were sacrificed after 15,30,45 days consequently.

The amount of new formed bone and the grafts remnants were investigated.

Results: material (A) showed a higher level of bone formation followed by material (B) after 30 days.

Statistically significant differences were observed between graft materials and controls after 30 and 45 days .

Conclusion: eggshell’s derived calcium carbonate is a biocompatible materials which has the ability to enhance bone formation.

a significant difference was observed between grafted and non-grafted sites after 30 days.

This ability can be increased by adding growth factors to the grafting material