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Clinical complications of hemoglobinopathies in western Saudi Arabia and the need for specialized care centers
Other Title(s)
المضاعفات الإكلينيكية لدى مرضى الأنيميا المنجلية و الثلاسيميا بالمنطقة الغربية من المملكة العربية السعودية و الحاجة إلى مراكز رعاية متخصصة
Joint Authors
Badawi, Maha Abd al-Razzaq
Ghunaym, Abd al-Rahman Husam al-Din
Jamjum, Ahmad Asim
Sahli, Ahmad Nayif
al-Masudi, Thanayyan Muhammad
Zahir, Jalilah Faysal
Adam, Suhayr Said
Hindawi, Salwa Ibrahim
Source
Journal of King Abdulaziz University : Medical Sciences
Issue
Vol. 26, Issue 1 (31 Mar. 2019), pp.29-36, 8 p.
Publisher
King Abdulaziz University Scientific Publishing Center
Publication Date
2019-03-31
Country of Publication
Saudi Arabia
No. of Pages
8
Main Subjects
Abstract EN
In the absence of specialized care centers for hemoglobinopathies in Saudi Arabia, there are insuffi cient data on prevalence of clinical complications in this population.
This is a retrospective record review about the clinical complications associated with hemoglobinopathies at King Abdulaziz University Hospital, for patients followed between January 1st 2010 through June 30th 2016.
A total of 349 patients were included, with a mean age of 25.45 years, including 266 with sickle cell disease and 80 with thalassemia.
Of those receiving regular transfusions, 17.5% developed alloantibodies, 16.6% tested positive for hepatitis C virus antibodies and the mean ferritin level was 2487 ng/ml.
Almost half of the patients were screened for renal disease, and more than 50% were found to have proteinuria.
Of 203 patients with recent echocardiograms, 15.8% had pulmonary hypertension.
Thirty-one (8.9%) patients died at a mean age of 28.5 years.
In conclusion, the prevalence of disease related complications is high in hemoglobinopathies.
Our results reiterate the need for specialized care hemoglobinopathy centers, which can further improve patient outcomes.
American Psychological Association (APA)
Badawi, Maha Abd al-Razzaq& Adam, Suhayr Said& Ghunaym, Abd al-Rahman Husam al-Din& Jamjum, Ahmad Asim& Sahli, Ahmad Nayif& Zahir, Jalilah Faysal…[et al.]. 2019. Clinical complications of hemoglobinopathies in western Saudi Arabia and the need for specialized care centers. Journal of King Abdulaziz University : Medical Sciences،Vol. 26, no. 1, pp.29-36.
https://search.emarefa.net/detail/BIM-933943
Modern Language Association (MLA)
Badawi, Maha Abd al-Razzaq…[et al.]. Clinical complications of hemoglobinopathies in western Saudi Arabia and the need for specialized care centers. Journal of King Abdulaziz University : Medical Sciences Vol. 26, no. 1 (2019), pp.29-36.
https://search.emarefa.net/detail/BIM-933943
American Medical Association (AMA)
Badawi, Maha Abd al-Razzaq& Adam, Suhayr Said& Ghunaym, Abd al-Rahman Husam al-Din& Jamjum, Ahmad Asim& Sahli, Ahmad Nayif& Zahir, Jalilah Faysal…[et al.]. Clinical complications of hemoglobinopathies in western Saudi Arabia and the need for specialized care centers. Journal of King Abdulaziz University : Medical Sciences. 2019. Vol. 26, no. 1, pp.29-36.
https://search.emarefa.net/detail/BIM-933943
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references : p. 33-35
Record ID
BIM-933943