The photo biological effect of low level laser therapy on serum level of leptin, cholesterol and triglycerides in overweight and obese females

Abstract EN

The use of low level laser for body contouring and weight reduction depends on the photochemical non thermal effect of laser light on the adipose tissue.

LLLT was reported to liquefy or release stored fat in adipocytes by the opening of specialized yet not identified cell membrane-associated pores after a brief treatment The concentration of leptin in adipose tissue and serum closely parallel the mass of adipose tissue and adipocyte size and triglycerides content.

Thus, leptin increases in obesity and falls with weight loss.

The current study was conducted to evaluate the effect of the low level laser therapy (LLLT) on leptin hormone, Cholesterol and triglyceride in both overweight and obese females.

Twenty women were included in this study.

Their ages ranged from 30-40 years.

They were divided into two equal groups.

Group A (Overweight group): included 10 females with BMI between 25and 29.9Kg/m2 -Group B (Obese group): included 10 females with BMI ≥ 30.

Both groups received LLL to the abdomen using laser scanner for uniform distribution of the beam above and below the umbilicus.

Duration of treatment was 30 minutes, 2 times per week for 8 weeks as a total period of treatment.

Serum level of leptin was estimated by radioimmunoassay (RIA).

As regards serum cholesterol and triglyceride they were determined by enzymatic colorimetric test.

Biochemical assessments were done before and after treatment.

Results of the present study showed that in the overweight group laser treatment resulted in highly significant reduction in leptin serum level accompanied by highly significant increase in serum triglycerides level.

Meanwhile, the increase in cholesterol level was insignificant.

As regards the obese group, alteration in serum leptin level caused by laser treatment was not significant.

In this group the increase in triglycerides and cholesterol serum levels after treatment were highly significant