Cinnamon (Cinnamomum zeylanicum N)‎ attenuates hepatic and cardiac tissues injury induced by gamma radiation in male albino rats

Abstract EN

The purpose of this study was to investigate the protective role of cinnamon; a spice rich in eugenol, cinnamic acid and cinnamic aldehyde, against tissue injuries induced by gamma irradiation.

Moreover, the effect of time of cinnamon aqueous extact (aq.extr).administration was evaluated.

Cinnamon aq.extr.

(200mg/Kg body weight) was administered to male albino rats via gavages during 15 successive days or 40 successive days before whole body exposure to gamma rays (3Gy).

The animals were sacrificed the 3rd day post-irradiation.

The results obtained revealed that the administration of cinnamon aq.extr.

during 15 successive days or 40 successive days before irradiation has significantly attenuated hepatic and cardiac tissue injuries.

Necrosis, apoptosis, cell death and rupture of cell membrane in both tissues were less severe.

However, the protection was better when cinnamon aq.extr.was administered for 40 successive days before irradiation.

It could be concluded that taking adequate amount of cinnamon aq.extr.

for a long time would protect hepatic and cardiac tissues from radiation-induced damage.