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Maternal and fetal risk factors associated with hypospadias in a sample of Iraqi boys
Joint Authors
al-Tamimi, Sayf H.
al-Qurayshi, Firas S.
Naji, Asil A.
Source
Issue
Vol. 16, Issue 3 (30 Sep. 2019), pp.174-178, 5 p.
Publisher
University of Babylon College of Medicine
Publication Date
2019-09-30
Country of Publication
Iraq
No. of Pages
5
Main Subjects
Abstract EN
Background: Hypospadias is one of the most common congenital anomalies among boys.
The exact causes of this anomaly are not clearly defined yet.
However, many of the risk factors have been identified in different ethnic groups.
Objective: The objectives of this study are to evaluate the maternal‑ and fetal‑related risk factors for hypospadias in a sample of Iraqi patients.
Materials and Methods: This case–control study included 42 boys with hypospadias cases and other 42 age‑matched boys free from any genital anomalies as a control group.
Maternal data, including age, parity, body mass index, hypertension, diabetes mellitus (DM), the use of assisted reproduction techniques (ART), level of education, consanguinity, and residence; and infant‑related factors.
Logistic regression analysis was used to predict the risk of each variable through the calculation of odds ratio (OR) and its corresponding 95% of confidence interval (CI).
Results: Three maternal factors were found to be associated significantly with increased risk of hypospadias.
These were maternal age >33 years (OR = 3.08, 95% CI = 1.02–9.26, P = 0.045), consanguineous marriage (OR = 3.0, 95% CI = 1.02–8.8, P = 0.045), and rural residence (OR = 2.64, 95% CI = 1.04–6.73, P = 0.041).
Hypertension, DM, and using ART were more frequent among mothers of cases than controls; however, the differences were not significant.
For fetal‑related factors, infants with low‑birth weight (LBW) were more frequent among cases than controls (40.48% vs.
19.05%), with a statistically significant difference (OR = 2.89, 95% CI = 1.08–7.75, P =0.035).
Of note, twins were more frequent among cases than controls; however, this difference was not statistically significant (P = 0.074).
Conclusions: These results highly suggest the critical role of advanced maternal age, consanguinity, rural residence, and infant LBW, as predisposing factors for the occurrence of hypospadias among Iraqi boys.
American Psychological Association (APA)
al-Tamimi, Sayf H.& al-Qurayshi, Firas S.& Naji, Asil A.. 2019. Maternal and fetal risk factors associated with hypospadias in a sample of Iraqi boys. Medical Journal of Babylon،Vol. 16, no. 3, pp.174-178.
https://search.emarefa.net/detail/BIM-935534
Modern Language Association (MLA)
al-Tamimi, Sayf H.…[et al.]. Maternal and fetal risk factors associated with hypospadias in a sample of Iraqi boys. Medical Journal of Babylon Vol. 16, no. 3 (Jul. / Sep. 2019), pp.174-178.
https://search.emarefa.net/detail/BIM-935534
American Medical Association (AMA)
al-Tamimi, Sayf H.& al-Qurayshi, Firas S.& Naji, Asil A.. Maternal and fetal risk factors associated with hypospadias in a sample of Iraqi boys. Medical Journal of Babylon. 2019. Vol. 16, no. 3, pp.174-178.
https://search.emarefa.net/detail/BIM-935534
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references : p. 177-178
Record ID
BIM-935534