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Phylogenetic analysis and immunohematological response associated with two commercially available vaccines against canine distemper and canine parvovirus
Joint Authors
Dawud, Ali
Nayil, Muhammad
al-Sayfi, Ahmad Mahmud
Musa, Walid M.
Salamah, Akram
Zayid, Atiyyah
Qamar, Ahmad
Badr, Yasin
al-Tayyib, Hind
Hildreth III, B. E.
Zaghawi, Ahmad
Source
Veterinary Medicine and Public Health Journal
Issue
Vol. 1, Issue 1 (31 Jan. 2020), pp.5-14, 10 p.
Publisher
Refaad Center for Studies and Research
Publication Date
2020-01-31
Country of Publication
Jordan
No. of Pages
10
Main Subjects
Topics
Abstract EN
Canine distemper and parvovirus infections are amongst of the most important infectious diseases of dogs.
yntneceR, the range of reports of vaccinated dogs that developed canine distemper and parvovirus infections have multiplied throughout the world.
The goals of this study were to evaluate the immune and hematological responses against canine distemper virus (CDV) and canine parvovirus (CPV) after vaccination using two commercially available vaccines.
In addition, the antigenic differences between the vaccine strains of CDV and CPV and the current wild-type strains were analyzed to determine possible relationships between these vaccine strains and recent field outbreaks in vaccinated populations.
The immune response of both vaccines was determined using serum neutralization and Dot-ELISA.
Specific neutralizing antibodies against canine distemper and parvovirus were present in the sera of dogs three weeks after the initial vaccination for both vaccines.
Peak antibody titers were documented from the second month post vaccination.
Both vaccines were demonstrated to be safe and stimulate a humoral immune response.
Results of serum neutralization test and Dot-ELISA were closely similar and correlated with each other.
Genetic variations between strains included in both commercial vaccines and circulating wild-type strains suggest that variant strains are most likely responsible for field outbreaks of CDV and CPV in vaccinated dogs.
American Psychological Association (APA)
Nayil, Muhammad& Zaghawi, Ahmad& Zayid, Atiyyah& al-Sayfi, Ahmad Mahmud& Qamar, Ahmad& Salamah, Akram…[et al.]. 2020. Phylogenetic analysis and immunohematological response associated with two commercially available vaccines against canine distemper and canine parvovirus. Veterinary Medicine and Public Health Journal،Vol. 1, no. 1, pp.5-14.
https://search.emarefa.net/detail/BIM-937062
Modern Language Association (MLA)
Nayil, Muhammad…[et al.]. Phylogenetic analysis and immunohematological response associated with two commercially available vaccines against canine distemper and canine parvovirus. Veterinary Medicine and Public Health Journal Vol. 1, no. 1 (Jan. 2020), pp.5-14.
https://search.emarefa.net/detail/BIM-937062
American Medical Association (AMA)
Nayil, Muhammad& Zaghawi, Ahmad& Zayid, Atiyyah& al-Sayfi, Ahmad Mahmud& Qamar, Ahmad& Salamah, Akram…[et al.]. Phylogenetic analysis and immunohematological response associated with two commercially available vaccines against canine distemper and canine parvovirus. Veterinary Medicine and Public Health Journal. 2020. Vol. 1, no. 1, pp.5-14.
https://search.emarefa.net/detail/BIM-937062
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references : p. 11-14
Record ID
BIM-937062