Effect of hepatoprotective role evaluation of Hibiscus rosa-sinensis leaves and pomegranate (Punica granatum) peels AQ ueous extracts on male albino rats
Other Title(s)
تقييم الدور الوقائي الكبدي للمستخلصات المائية لأوراق نبات الهيبكس روزا سننسس و قشور الرمان في الفئران البيضاء
Author
al-Sayyid, Mahmud Shukri Sadiq
Source
Zagazig Journal for Agricultural Researches
Issue
Vol. 45, Issue 1 (28 Feb. 2018), pp.349-362, 14 p.
Publisher
Zagazig University Faculty of Agriculture
Publication Date
2018-02-28
Country of Publication
Egypt
No. of Pages
14
Main Subjects
Abstract EN
The cuiTent study sought to investigate the influence of individual and combined in different levels of natural products (aqueous extract of Hibiscus rosa-sinensis leaves-AEHRS.
aqueous extract of pomegranate (punica granarum) peels-AEPP- and mixture of both) in order to assess the potency of the previous aqueous natural products extracts against liver diseases (oxidative stress).
The serum aspartate aminotransferase (AST); alanine aminotransferase (ALT); alkaline phosphatase (ALP) and total bilirubin were assayed after 7, 14 and 21 days.
Male albino rats were used in this study which contained twelve groups, six animals each.
Group (I) normal control without any extract of AEHRS leaves or AEPP.
Group (II) injected with carbon tetrachloride(CCLj) induced oxidative stress in rats (CCU control-treated group).Groups (III)leaves extract 250 mg / kg b.wt.
of HRS.
(IV) leaves extract 500 mgkg b.wt.
of HRS.
(V) leaves extract 750 mglg b.wt.
of HRS.
(VI) peels extract 100 mg / kg b.wt.
of P.granatum.
(VII) peels extract 200 mgkg b.wt.
of P.granamm.
(VIE) peels extract 300 mg / kg b.wt.
of P.granarum.
(IX) AEHRS leaves and AEPP mixture 125 / 125 mgkg b.wt.
(X) AEHRS leaves and AEPP mixture 225/225 mgkg b.wt.
(XI) AEHRS leaves and AEPP mixture 350/350 mg'kg b.wt .In addition, one group for carbon tetrachloride rats group which treated with AEHRS leaves and AEPP mixture 400400 mgkg b.wt (XII).
respectively.
All groups were received the extracts daily oral except for normal control group (I).
The present data demonstrate that AEHRS leaves.
AEPP and their mixtures significantly attenuated liver functions parameters in serum when comparing with normal control group (I) and intoxicated control group (II).
These findings suggest that AEHRS leaves.
AEPP and mixtures of both have a potent hepatoprotective effect, where ALT.
AST.
ALP and total bilirubin decreased from 29.55± 1.15 to 20.15 ± 0.87U / 1.
from 47.97 ± 1.66 to 30.99±1.78U/L from 305.96±35.61 to 170.55±46.42 U / l and from 3.11±0.02 to 2.21 ± 0.81 mg'dl respectively.
American Psychological Association (APA)
al-Sayyid, Mahmud Shukri Sadiq. 2018. Effect of hepatoprotective role evaluation of Hibiscus rosa-sinensis leaves and pomegranate (Punica granatum) peels AQ ueous extracts on male albino rats. Zagazig Journal for Agricultural Researches،Vol. 45, no. 1, pp.349-362.
https://search.emarefa.net/detail/BIM-938643
Modern Language Association (MLA)
al-Sayyid, Mahmud Shukri Sadiq. Effect of hepatoprotective role evaluation of Hibiscus rosa-sinensis leaves and pomegranate (Punica granatum) peels AQ ueous extracts on male albino rats. Zagazig Journal for Agricultural Researches Vol. 45, no. 1 (2018), pp.349-362.
https://search.emarefa.net/detail/BIM-938643
American Medical Association (AMA)
al-Sayyid, Mahmud Shukri Sadiq. Effect of hepatoprotective role evaluation of Hibiscus rosa-sinensis leaves and pomegranate (Punica granatum) peels AQ ueous extracts on male albino rats. Zagazig Journal for Agricultural Researches. 2018. Vol. 45, no. 1, pp.349-362.
https://search.emarefa.net/detail/BIM-938643
Data Type
Journal Articles
Language
English
Record ID
BIM-938643