A comparative study for GLP-1 levels in Iraqi diabetic patients with hyper and hypothyroidism
Joint Authors
al-Rabii, Zaynab Munib Malik
al-Taimari, Usamah Salman
al-Ubaydi, Huda Ahmad
Source
al-Kufa University Journal for Biology
Issue
Vol. 10, Issue 1 (30 Apr. 2018), pp.62-71, 10 p.
Publisher
University of Kufa Faculty of Science Department of live Sciences
Publication Date
2018-04-30
Country of Publication
Iraq
No. of Pages
10
Main Subjects
Abstract EN
The current study aimed to determine GLP-1 levels in hyper and hypothyroidism disease with diabetic and compared the results with a control group.
The study also aimed to find the relationship for GLP-1 with (TSH, T3and insulin) in patients groups.
The study involved 30 subjects with hyperthyroidism and diabetic as group 1(G1), and 30 subjects hypothyroidism patients with diabetes as group 2 (G2) to 30 healthy controls as group 3 (G3).
The subjects were matched aged of (40-65 years).
Serum used in determination T3, TSH, FBG and insulin in the control and patients groups, the BMI and IR were also calculated.
Results showed highly significant increase in T3 levels in G1 contrast to G3 while there are no significant decreasing was found in G2 contrast to G3.Results in this study revealed highly significant decreasing in TSH levels in G1 contrast to G3 with highly significant increase in G2 comparing to G3.
Results illustrate levels of FBG in all studied groups, which showed highly significant increase in FBG in G1 and G2 comparing to G3.
Results showed highly significant increase in insulin levels in G1 contrast to G3 while there are no significant different observed in G1 contrast to G2.
Results, also, showed highly significant increasing in GLP-1 in G1 and G2 when compared to G3.Correlation relation of GLP-1with T3, TSH and insulin were studied.
Result revealed significant positive correlation between GLP-1 and T3 in G3 (P≤0.5, r = 0.350) while a significant negative correlation was observed in G1 and G2 (P≤0.05, r = -.047, r = -0.55).
Results revealed significant positive correlation in G3 between TSH and T3 (P≤0.05, r = -.055) while a significant negative correlation (P≤0.05, r = -.047, r =.386) was observed in G1 and G2.
Study also showed the correlation relation between GLP-1 and insulin there are no significant positive relation was seen in G3 (P˃0.05, r = 0.083), while showed highly significant positive correlation in G1 and G2 (r = 0.55, r = 0.344).
It is Concluded from this study that GLP-1 can be used as a marker in diagnostic and monitoring the development in diabetes to its complication in these patients.
American Psychological Association (APA)
al-Rabii, Zaynab Munib Malik& al-Taimari, Usamah Salman& al-Ubaydi, Huda Ahmad. 2018. A comparative study for GLP-1 levels in Iraqi diabetic patients with hyper and hypothyroidism. al-Kufa University Journal for Biology،Vol. 10, no. 1, pp.62-71.
https://search.emarefa.net/detail/BIM-939763
Modern Language Association (MLA)
al-Ubaydi, Huda Ahmad…[et al.]. A comparative study for GLP-1 levels in Iraqi diabetic patients with hyper and hypothyroidism. al-Kufa University Journal for Biology Vol. 10, no. 1 (2018), pp.62-71.
https://search.emarefa.net/detail/BIM-939763
American Medical Association (AMA)
al-Rabii, Zaynab Munib Malik& al-Taimari, Usamah Salman& al-Ubaydi, Huda Ahmad. A comparative study for GLP-1 levels in Iraqi diabetic patients with hyper and hypothyroidism. al-Kufa University Journal for Biology. 2018. Vol. 10, no. 1, pp.62-71.
https://search.emarefa.net/detail/BIM-939763
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references : p. 69-71
Record ID
BIM-939763