The reactivity of anti-HCMV IgM to various specific HCMV antigens among pregnant women in Kirkuk
Joint Authors
Sadun, Isra Hashim
Qadir, Sattar Muhammad
Hamadah, Dhikria Ahmad
Source
Kirkuk University Journal-Scientific Studies
Issue
Vol. 13, Issue 4 (31 Dec. 2018), pp.57-68, 12 p.
Publisher
Kirkuk University College of Science
Publication Date
2018-12-31
Country of Publication
Iraq
No. of Pages
12
Main Subjects
Abstract EN
Human Cytomegalovirus (HCMV) is a DNA virus of the Betaherpesvirinae subfamily and Herpesviridae family.
HCMV is a leading cause of congenital infections throughout the world.
This study was carried out in Kirkuk governorate from July 2017 to January 2018,aimed at studying there activity of anti-HCMV IgM to various specific HCMV antigens among 180 pregnant women attending hospitals, primary health care centers and some private medical laboratories.
The pregnant women were examined for HCMV-IgM seroprevalence using Electro-chemo-luminescence(ECLIA) technique then examined their reactivity for specific HCMV antigens using line immune assay.
The rates of HCMV-IgM seropositive were 22 (12.22 %).
Regarding the reactivity of determined HCMV-IgM against various HCMV antigens, the rates 14 (63.63%), 13(59.09%), 21(95.45%), 15(68.18%), 21(95.45%) and 16(72.72%) were seropositive for HCMV IE1, CM2, p150, p65, gB1 and gB2 antigens, respectively.
Concerning the band intensity of HCMV-IgM reactions with HCMV antigens, the rates of (+++) were higher than other band intensity for all antigens with highest rate for gB1 antigen (85.71%).
So, the highest rate of HCMV-IgM reaction with the number of antigens was 40.90% for three antigens at the same time.
In conclusion, the highest rate of HCMV-IgM in pregnant women was for gB1and p150 antigens; while the highest rate of intensity reaction was (+++)and the highest rate of HCMV-IgM ability for reaction was for three antigens at the same time
American Psychological Association (APA)
Qadir, Sattar Muhammad& Sadun, Isra Hashim& Hamadah, Dhikria Ahmad. 2018. The reactivity of anti-HCMV IgM to various specific HCMV antigens among pregnant women in Kirkuk. Kirkuk University Journal-Scientific Studies،Vol. 13, no. 4, pp.57-68.
https://search.emarefa.net/detail/BIM-944728
Modern Language Association (MLA)
Qadir, Sattar Muhammad…[et al.]. The reactivity of anti-HCMV IgM to various specific HCMV antigens among pregnant women in Kirkuk. Kirkuk University Journal-Scientific Studies Vol. 13, no. 4 (Dec. 2018), pp.57-68.
https://search.emarefa.net/detail/BIM-944728
American Medical Association (AMA)
Qadir, Sattar Muhammad& Sadun, Isra Hashim& Hamadah, Dhikria Ahmad. The reactivity of anti-HCMV IgM to various specific HCMV antigens among pregnant women in Kirkuk. Kirkuk University Journal-Scientific Studies. 2018. Vol. 13, no. 4, pp.57-68.
https://search.emarefa.net/detail/BIM-944728
Data Type
Journal Articles
Language
English
Notes
Record ID
BIM-944728