Synthesis and identification of four membered rings heterocyclic compounds derived from trimethoprim

Abstract EN

This study includs the preparation and identification of four membered rings Hetrocyclic Compounds derived from Trimethoprim by reaction Schiffs, bases(1a-h)( prepared by reaction some aromatic aldehyde with Trimethoprim using Microwave technique) with chloro acetyl chlorid in the presence of triethylamine , the prepared compounds were identified by I.R spectroscopy and some of them by NMR spectroscopy and C.H.N.S micro analysis.