Study the effect of isolated alkaloid from Haloxylon Salicornicum plant on some hematological and biochemical parameters in gastric ulceration rabbits induced by indomethacin
Other Title(s)
دراسة تأثير القلويد المعزول من نبات الشنان على بعض المعايير الدموية و البايوكيميائية في الارانب المصابة بالقرحة المعدية المستحدثة بواسطة الاندوميثاسين
Joint Authors
Jabbar, Nur Abd al-Amir
Haddad, Batul Salih Mahdi
al-Said, Arwa Hamid Mahmud
Source
Basrah Journal of Veterinary Research
Issue
Vol. 18, Issue 1 (30 Jun. 2019), pp.36-55, 20 p.
Publisher
University of Basrah College of Veterinary Medicine
Publication Date
2019-06-30
Country of Publication
Iraq
No. of Pages
20
Main Subjects
Abstract EN
This study was undertaken to isolate alkaloids from Haloxylon Salicornicum plant to show the curative effect after short-term daily orall administration for 10 days (300 mg/Kg B.W.) on gastric ulcer,hematological parameters and some biochemical parameters in gastric ulceration rabbits induced by indomethacin.Moreover,some qualitative chemical analysis,thin layer chromatography,UVspectroscopy and FTIR spectroscopy were used to identify alkaloid compound .Rabbits were divided randomly into three groups,6 rabbits in each.Group one received 3 ml normal saline orally (control group).Group two was treated with indomethacin (75 mg/Kg B.W.) (gastric ulceration group).Third group gastric ulceration rabbits post-treated with isolated alkaloid (300 mg/Kg B.W.).The results of the present study indicated that isolated alkaloid has Rf= 0.86,high significant decreased (p≤0.001) in RBC,Hb,PCVand mucin,(P ≤ 0.01) in MCHC and PH,no significant difference (P ≥ 0.05) in MCH in gastric ulceration rabbits compared with control group and observed high significant increased (p≤0.001) in MCV, MDA and gastric juce volume,WBCcount appeared high significant increased (P≤0.01).While, observed high significant increased(P≤ 0.001) in Hb,PCVand mucin,(P≤ 0.01) in RBC,MCHC and pH.Significant increased(P≤0.05) in MCH after treated with isolated alkaloid and high significantly decrease (P ≤ 0.001)in MCV,gastric juce volume and MDA
American Psychological Association (APA)
Jabbar, Nur Abd al-Amir& al-Said, Arwa Hamid Mahmud& Haddad, Batul Salih Mahdi. 2019. Study the effect of isolated alkaloid from Haloxylon Salicornicum plant on some hematological and biochemical parameters in gastric ulceration rabbits induced by indomethacin. Basrah Journal of Veterinary Research،Vol. 18, no. 1, pp.36-55.
https://search.emarefa.net/detail/BIM-946063
Modern Language Association (MLA)
Jabbar, Nur Abd al-Amir…[et al.]. Study the effect of isolated alkaloid from Haloxylon Salicornicum plant on some hematological and biochemical parameters in gastric ulceration rabbits induced by indomethacin. Basrah Journal of Veterinary Research Vol. 18, no. 1 (2019), pp.36-55.
https://search.emarefa.net/detail/BIM-946063
American Medical Association (AMA)
Jabbar, Nur Abd al-Amir& al-Said, Arwa Hamid Mahmud& Haddad, Batul Salih Mahdi. Study the effect of isolated alkaloid from Haloxylon Salicornicum plant on some hematological and biochemical parameters in gastric ulceration rabbits induced by indomethacin. Basrah Journal of Veterinary Research. 2019. Vol. 18, no. 1, pp.36-55.
https://search.emarefa.net/detail/BIM-946063
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references : p. 51-55
Record ID
BIM-946063