The effect of using combined oral ethinyl estradiol and levonorgestrel in the resolution of menstrual pattern disorder and functional ovarian cyst
Other Title(s)
تأثير استخدام حبوب منع الحمل الفموية المركبة إيثينيل إستراديول و ليفونورجستريل في حل اضطراب نمط الحيض و الأكيس المبيضي الوظيفي
Joint Authors
Muhammad, Sana Jafar
Atut, Maha
Agha, Qutaybah Ahmad al-Khamis
Khammas, Sura Yasir Taha
Ismail, Najla Sadi
Source
Annals of the College of Medicine Mosul
Issue
Vol. 41, Issue 2 (30 Jun. 2019), pp.190-196, 7 p.
Publisher
University of Mosul College of Medicine-Mosul
Publication Date
2019-06-30
Country of Publication
Iraq
No. of Pages
7
Main Subjects
Topics
Abstract EN
Objectives: To evaluate the usefulness of combined oral contraceptives (ethinyl estradiol and levonorgestrel) in resolving menstrual pattern disorder in reproductive-age women with a functional ovarian cyst in Iraq.
Method:A longitudinal (before and after) , interventional study was used.
Data were collected at a single obstetrics and gynaecology outpatient clinic in Mosul City, Iraq.
Participants: A sample of 96 women aged between 15 and 45 years participated in the study.
Participants diagnosed with ovarian cysts were treated using an oral administration of contraceptive pills (combination of ethinyl estradiol, 0.03 mg, and levonorgestrel, 0.15 mg) on a daily basis for a treatment duration of 2 months.
The Outcome Measures are Menstrual pattern disorders (dysmenorrhea, irregular menstrual cycle, and amenorrhea) and cyst dimensions were recorded.
Results: After one therapy cycle, a statistically significant disappearance of menstrual pattern disorder was observed (p=0.000).
Cyst resolution was observed in 89.58% of the patients (n=86), while mean ovarian cyst size fell from 4.452 ± 1.0603 cm at the start of therapy to 0 .451 ± 1.5613 cm(p = 0.000).
5 of the 10 persistent cysts disappeared after the second cycle (2 months after the start of therapy) and complete cyst resolution was 94.8% (n = 91) after two cycles.
This indicated a further significant reduction of mean ovarian cyst size to 0.335 ± 1.4684 cm.
However, no significant difference was observed between mean cyst size in the first and second months of treatment (p=0.329).
Conclusion: Combined oral contraceptives (ethinyl estradiol and levonorgestrel pills) are effective in relieving dysmenorrhea, irregular menstrual cycle, and amenorrhea.
They also hasten the disappearance of functional ovarian cysts, and are associated with high rates of success in patients with functional ovarian cysts.
American Psychological Association (APA)
Ismail, Najla Sadi& Muhammad, Sana Jafar& Atut, Maha& Agha, Qutaybah Ahmad al-Khamis& Khammas, Sura Yasir Taha. 2019. The effect of using combined oral ethinyl estradiol and levonorgestrel in the resolution of menstrual pattern disorder and functional ovarian cyst. Annals of the College of Medicine Mosul،Vol. 41, no. 2, pp.190-196.
https://search.emarefa.net/detail/BIM-946670
Modern Language Association (MLA)
Ismail, Najla Sadi…[et al.]. The effect of using combined oral ethinyl estradiol and levonorgestrel in the resolution of menstrual pattern disorder and functional ovarian cyst. Annals of the College of Medicine Mosul Vol. 41, no. 2 (Jun. 2019), pp.190-196.
https://search.emarefa.net/detail/BIM-946670
American Medical Association (AMA)
Ismail, Najla Sadi& Muhammad, Sana Jafar& Atut, Maha& Agha, Qutaybah Ahmad al-Khamis& Khammas, Sura Yasir Taha. The effect of using combined oral ethinyl estradiol and levonorgestrel in the resolution of menstrual pattern disorder and functional ovarian cyst. Annals of the College of Medicine Mosul. 2019. Vol. 41, no. 2, pp.190-196.
https://search.emarefa.net/detail/BIM-946670
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references : p. 169
Record ID
BIM-946670