استخدام بكتريا Lactobacillus rhamnosus GG ضد الإصابة بداء الأكياس العدرية الثانوي في الفئران السويسرية BALB c

Abstract EN

The present study investigated the effect of probiotic bacteria lactobacillus GG (13×105 CFU/0.1ml) on the immune response of Swiss BALB/c mice (injected intraperitoneally), against experimental Infection with protoscoleces of Echinococcus granulosus (Postinfection), in comparison with the control group (mice injected with protoscoleces only) for 2-5 months.

Another experimental group of mice inoculated (orally) with L.rhamnosus GG (8×107 CFU/0.1ml) preinfection with protoscoleces for 3 months.

Depending on many criteria including numbers, weights, diameters of developed hydtid cysts, and the percentage of their reduction, the results revealed a significant decrease (P ≤ 0.05) (P ≤ 0.01) in numbers, weights and diameters of hydatid cysts in treated mice, expressed by the percentage reduction elevation of their numbers to (98%) in mice treated intraperitoneally (2-5 months) post infection, and 95% in mice treated orally 3 months pre infection, as compared with the control groups.