Spectrophotometric determination of oxymetazoline hydrochloride in pure and pharmaceutical preparations using diazo-coupling reaction
Other Title(s)
التقدير الطيفي للاوكسيميتازولين هيدروكلوريد بشكله الحر و في مستحضراته الصيدلانية باستخدام تفاعلات الأزوتة و الاقتران
Joint Authors
al-Ghabsha, Thabit S.
Zakariyya, Rawa Abd al-Halim
Ubayd Agha, Asil N.
Source
al-Tarbiyah wa-al-Ilm : Majallat ilmiyah lil-Buhuth al-Ilmiyah al-Asasiyah
Issue
Vol. 28, Issue 4 (31 Dec. 2019), pp.225-232, 8 p.
Publisher
University of Mosul College of Education for Pure Science
Publication Date
2019-12-31
Country of Publication
Iraq
No. of Pages
8
Main Subjects
Abstract EN
ccurate and simple spectrophotometric method has been suggested for the determination of oxymetazoline hydrochloride (OMCl) in aqueous solution is developed.
The present process included coupling of OMCl with diazotized sulphanilic acid reagent in the presence of sodium hydroxide.
The orange colored azo dye formed very stable and soluble in water gives maximum absorption at 496 nm.
The lineratey is obeyed over the range 20 – 400 g / 25 ml (0.8 –16μg.ml-1) the molar absorptivity is equate to 2.30 104 l.mol-1cm-1.
The proposed method has been used to the determination of OMCl in two formulations with satisfactories results
American Psychological Association (APA)
al-Ghabsha, Thabit S.& Zakariyya, Rawa Abd al-Halim& Ubayd Agha, Asil N.. 2019. Spectrophotometric determination of oxymetazoline hydrochloride in pure and pharmaceutical preparations using diazo-coupling reaction. al-Tarbiyah wa-al-Ilm : Majallat ilmiyah lil-Buhuth al-Ilmiyah al-Asasiyah،Vol. 28, no. 4, pp.225-232.
https://search.emarefa.net/detail/BIM-948522
Modern Language Association (MLA)
al-Ghabsha, Thabit S.…[et al.]. Spectrophotometric determination of oxymetazoline hydrochloride in pure and pharmaceutical preparations using diazo-coupling reaction. al-Tarbiyah wa-al-Ilm : Majallat ilmiyah lil-Buhuth al-Ilmiyah al-Asasiyah Vol. 28, no. 4 (2019), pp.225-232.
https://search.emarefa.net/detail/BIM-948522
American Medical Association (AMA)
al-Ghabsha, Thabit S.& Zakariyya, Rawa Abd al-Halim& Ubayd Agha, Asil N.. Spectrophotometric determination of oxymetazoline hydrochloride in pure and pharmaceutical preparations using diazo-coupling reaction. al-Tarbiyah wa-al-Ilm : Majallat ilmiyah lil-Buhuth al-Ilmiyah al-Asasiyah. 2019. Vol. 28, no. 4, pp.225-232.
https://search.emarefa.net/detail/BIM-948522
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references : p. 232
Record ID
BIM-948522