Synthesis and characterization of a new series of arylidene compounds from 2-iminothiazolidine-4-one derivatives
Joint Authors
Abd Allah, Venos Said
Aziz, Hashim Jalal
Source
ZANCO Journal of Pure and Applied Sciences
Issue
Vol. 31, Issue 4 (sup) (31 Aug. 2019), pp.97-108, 12 p.
Publisher
Salahaddin University-Erbil Department of Scientific Publications
Publication Date
2019-08-31
Country of Publication
Iraq
No. of Pages
12
Main Subjects
Abstract EN
The present work describes the synthesis and characterization of a new series of arylidene compounds from 2-iminothiazolidine -4-one which includes the preparation of 2-chloro-N-(4-(6-methyl benzo [d] thiazol-2-yl) phenyl) acetamide which was prepared through the reaction of 4-(6-methylbenzothiazole-2-yl) benzyl amine with chloroacetyl chloride in dry benzene to afford 2-chloro-N-(4-(6-methyl benzo [d] thiazol-2-yl)phenyl) acetamide .
The later compound easily undergo cyclization reaction by potassium thiocyanate in dry acetone and results the formation of 2-imino-3-(4-(6-methylbenzo [d] thiazol-2-yl) phenyl) thiazolidin-4-one.
After cyclization let react with different aromatic aldehydes to produce 5-benzylidene-2-imino-3-(4)6-methyl benzo [d]thiazol-2-yl) phenyl) thiazolidin-4-one .
The FT-IR, 1H-NMR and 13C-NMR, 13C-DEPT-135, UV-Visible) spectra of the prepared compounds were confirmed the proposed structure, ultimately antimicrobial activity of the newly obtained compounds were tested against (Staphylococcus aureus ) (+ ve) , (Pseudomonas aeruginosa ) (-ve) and the results showed that most of the prepared compounds are sensitive against both types of test organisms in different activities.
American Psychological Association (APA)
Aziz, Hashim Jalal& Abd Allah, Venos Said. 2019. Synthesis and characterization of a new series of arylidene compounds from 2-iminothiazolidine-4-one derivatives. ZANCO Journal of Pure and Applied Sciences،Vol. 31, no. 4 (sup), pp.97-108.
https://search.emarefa.net/detail/BIM-949174
Modern Language Association (MLA)
Aziz, Hashim Jalal& Abd Allah, Venos Said. Synthesis and characterization of a new series of arylidene compounds from 2-iminothiazolidine-4-one derivatives. ZANCO Journal of Pure and Applied Sciences Vol. 31, no. 4 (Supplement) (2019), pp.97-108.
https://search.emarefa.net/detail/BIM-949174
American Medical Association (AMA)
Aziz, Hashim Jalal& Abd Allah, Venos Said. Synthesis and characterization of a new series of arylidene compounds from 2-iminothiazolidine-4-one derivatives. ZANCO Journal of Pure and Applied Sciences. 2019. Vol. 31, no. 4 (sup), pp.97-108.
https://search.emarefa.net/detail/BIM-949174
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references : p. 108
Record ID
BIM-949174