First case report of primary testicular diffuse large B-cell lymphoma from the western Region of Saudi Arabia
Joint Authors
Abd al-Badi, Ahmad
al-Basri, Abd al-Qadir
al-Qabalawi, Muhammad A.
Husayni, Akbar S.
al-Juhani, Abd al-Aziz R.
Source
Yemeni Journal for Medical Sciences
Issue
Vol. 13, Issue 1 (31 Dec. 2019), pp.35-38, 4 p.
Publisher
University of Science and Technology
Publication Date
2019-12-31
Country of Publication
Yemen
No. of Pages
4
Main Subjects
Topics
Abstract EN
Primary testicular lymphoma (PTL) represents 1-2% of all types of non-Hodgkin lymphomas (NHLs) and 1-10% of testicular neoplasms.
Up to the best of my knowledge, this is the first case of PTL of the diffuse large B-cell lymphoma (DLBCL) in a 60-year-old man presented with a painless mass in the left testis as revealed by physical examination in a tertiary care hospital in Al-Madinah Al-Munwarah in the western region of the Kingdom of Saudi Arabia (KSA).
Radiological examination revealed a large well-defined heterogeneous predominantly hypo-echoic mass with increased vascularity in the upper portion of the testis.
On the other hand, histopathological examination revealed a tumor involving the whole left testis, which was large (measuring 6 3.5 3.3 cm), solid and dark red with focal areas of hemorrhage and epididymal infiltration.
Immunohistochemistry showed positivity of leucocyte common antigen (LCA), pan B-cell marker (CD20) and negativity of pan T-cell marker (CD3).
Other immunohistochemical markers such as CD10, placental alkaline phosphatase (PLAP), cytokeratin, vimentin, desmin and S100 protein were also negative.
However, there was a marked expression of Ki67 and Bcl2 markers.
Accordingly, the diagnosis of DLBCL was established.
The tumor was classified as stage I according to the Ann Arbor system.
The case was treated by orchiectomy followed by prophylactic anthracycline-based chemotherapy and irradiation of the contralateral testis and central nervous system.
American Psychological Association (APA)
al-Basri, Abd al-Qadir& al-Qabalawi, Muhammad A.& Abd al-Badi, Ahmad& Husayni, Akbar S.& al-Juhani, Abd al-Aziz R.. 2019. First case report of primary testicular diffuse large B-cell lymphoma from the western Region of Saudi Arabia. Yemeni Journal for Medical Sciences،Vol. 13, no. 1, pp.35-38.
https://search.emarefa.net/detail/BIM-952780
Modern Language Association (MLA)
al-Basri, Abd al-Qadir…[et al.]. First case report of primary testicular diffuse large B-cell lymphoma from the western Region of Saudi Arabia. Yemeni Journal for Medical Sciences Vol. 13, no. 1 (2019), pp.35-38.
https://search.emarefa.net/detail/BIM-952780
American Medical Association (AMA)
al-Basri, Abd al-Qadir& al-Qabalawi, Muhammad A.& Abd al-Badi, Ahmad& Husayni, Akbar S.& al-Juhani, Abd al-Aziz R.. First case report of primary testicular diffuse large B-cell lymphoma from the western Region of Saudi Arabia. Yemeni Journal for Medical Sciences. 2019. Vol. 13, no. 1, pp.35-38.
https://search.emarefa.net/detail/BIM-952780
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references : p. 38
Record ID
BIM-952780