Biosynthesis of silver nanoparticles using (Carissa macrocarpa)‎ leaves extract and study its antibacterial activity

Abstract EN

Among all the nanoparticles synthesized; silver nanoparticles have attained special place in the area of nanotechnology because of their antimicrobial and medical applications.

In general; their syntheses involves the use of unsafe chemicals or costly physical methods.

However, the biological processes are making their ways in between and proving their advantages over them.

The use of plants and their extracts is one of the most valuable methods which are gaining concerns due to their imperative biological benefits.

Plants are not only beautiful but majestic, they are rich sources of various medicinally important substances.

In the presented work “one pot synthesis of silver nanoparticles” were described.

A simple, cost effective bio-reduction on the principle of “green synthesis” of silver nanoparticles using the Carrisiamacrocarpa leaves extract.

The aqueous silver ions were reduced to silver nanoparticles when exposed to leaves extract.

The bio-reduction and stabilization of so formed silver nanoparticles was monitored by UV-Vis spectrophotometry.

The synthesized silver nanoparticles were also characterized by various other techniques viz.

FTIR spectroscopy, XRD diffraction, SEM, and TEM.

Revealed that the synthesized silver nanoparticles were spherical in shape with a size of (38- 74 nm).

Biological evaluations of silver nanoparticles were also done against gram positive (Staphylococcus aureus) and gram negative bacteria (.Shigella) for their future applications in biomedicines especially for the treatment of wounds